Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 7/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 2/20 | 0.38 |
| ▸ | MMP9 | P14780 | 2/20 | 0.38 |
| ▸ | NOX4 | Q9NPH5 | 2/20 | 0.37 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
| ▸ | PPARD | Q03181 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5885620 | 0.76 | L3MBTL1 (0.48) | HTR6L3MBTL1POLBMEN1KMT2A | |
| SCHEMBL147442 | 0.76 | HTR6 (0.66) | HTR6L3MBTL1POLBMEN1KMT2A | |
| SCHEMBL5063774 | 0.74 | PPARD (0.55) | HTR6L3MBTL1POLBHDAC1HDAC6 | |
| SCHEMBL28685370 | 0.70 | HTR6 (0.56) | HTR6L3MBTL1POLBHDAC1HDAC6 | |
| SCHEMBL145051 | 0.69 | KCNH2 (0.43) | — | |
| SCHEMBL30075056 | 0.68 | HTR6 (0.53) | HTR6L3MBTL1POLBHDAC1HDAC6 | |
| SCHEMBL14631737 | 0.68 | HTR6 (0.53) | HTR6L3MBTL1POLBHDAC1HDAC6 | |
| SCHEMBL29425682 | 0.68 | HDAC1 (0.52) | HTR6L3MBTL1POLBHDAC1HDAC6 | |
| SCHEMBL28692303 | 0.68 | HDAC1 (0.52) | HTR6L3MBTL1POLBHDAC1HDAC6 | |
| SCHEMBL28037053 | 0.67 | HTR6 (0.63) | HTR6L3MBTL1POLBHDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080234349-A1 | PPAR active compounds | PLEXXIKON INC. | 2008-09-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080234349-A1 | PPAR active compounds | PPARG, PPARA, PPARD | HTR6 1985/4885L3MBTL1 3414/4885POLB 620/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.