Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.50 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.50 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.47 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.47 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.47 |
| ▸ | GGT1 | P19440 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | BACE1 | P56817 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4189748 | 0.85 | GAPDH (0.50) | ADORA3ADORA2AADORA1KDM4EALDH1A1 | |
| SCHEMBL27849556 | 0.81 | ADORA3 (0.55) | ADORA3ADORA2AADORA1KDM4EALDH1A1 | |
| SCHEMBL3728321 | 0.81 | KDM4E (0.58) | ADORA3ADORA2AADORA1KDM4EALDH1A1 | |
| Bicarbonate SCHEMBL9330276 | 0.80 | KDM4E (0.56) | ADORA3ADORA2AADORA1KDM4EALDH1A1 | |
| SCHEMBL16568061 | 0.80 | NCOA1 (0.41) | KDM4EALDH1A1PTGS2LMNAMAPK1 | |
| SCHEMBL8676657 | 0.79 | MAPK1 (0.60) | ADORA3ADORA2AADORA1KDM4EALDH1A1 | |
| SCHEMBL3792914 | 0.79 | ADORA3 (0.54) | ADORA3ADORA2AADORA1KDM4EALDH1A1 | |
| SCHEMBL5068620 | 0.78 | KDM4E (0.46) | KDM4EALDH1A1TDP1LMNAGAA | |
| SCHEMBL9138778 | 0.78 | KDM4E (0.54) | ADORA3ADORA2AADORA1KDM4EALDH1A1 | |
| SCHEMBL7895673 | 0.77 | INPPL1 (0.46) | KDM4EALDH1A1HSD17B10HPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008099904-A1 | SILANE COMPOUND, PRODUCTION METHOD THEREOF, AND RESIN COMPOSITION CONTAINING SILANE COMPOUND | NIPPON SHOKUBAI CO., LTD. (JP) | 2008-08-21 | — | — | WO | disclosed |