Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 2/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1338595 | 0.85 | MAPK1 (0.36) | ALDH1A1HSD17B10MAPK1HPGDBCL2L1 | |
| SCHEMBL27619931 | 0.85 | ABL1 (0.53) | MAPTBACE1HTR7 | |
| SCHEMBL18297950 | 0.82 | HSD11B1 (0.37) | ALDH1A1HSD17B10MAPK1HPGDBCL2L1 | |
| SCHEMBL10448876 | 0.82 | ALDH1A1 (0.52) | ALDH1A1HSD17B10MAPK1HPGDBCL2L1 | |
| SCHEMBL10581664 | 0.82 | CYP2A6 (0.40) | ALDH1A1HSD17B10MAPK1HPGDBCL2L1 | |
| SCHEMBL28562495 | 0.80 | MAPK1 (0.43) | ALDH1A1HSD17B10MAPK1HPGDBCL2L1 | |
| SCHEMBL6900861 | 0.79 | MAPK1 (0.42) | ALDH1A1HSD17B10MAPK1NPSR1ALOX15 | |
| SCHEMBL29947075 | 0.79 | MAPK1 (0.42) | ALDH1A1HSD17B10MAPK1NPSR1ALOX15 | |
| SCHEMBL29833702 | 0.78 | ALDH1A1 (0.46) | ALDH1A1HSD17B10MAPK1HPGDBCL2L1 | |
| SCHEMBL291792 | 0.78 | ALDH1A1 (0.46) | ALDH1A1HSD17B10MAPK1HPGDBCL2L1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008099904-A1 | SILANE COMPOUND, PRODUCTION METHOD THEREOF, AND RESIN COMPOSITION CONTAINING SILANE COMPOUND | NIPPON SHOKUBAI CO., LTD. (JP) | 2008-08-21 | — | — | WO | disclosed |