Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 1/20 | 0.59 |
| ▸ | TEK | Q02763 | 2/20 | 0.58 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 6/20 | 0.57 |
| ▸ | MEN1 | O00255 | 6/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.57 |
| ▸ | NPC1 | O15118 | 4/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | LCK | P06239 | 2/20 | 0.56 |
| ▸ | AURKA | O14965 | 1/20 | 0.56 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.56 |
| ▸ | MET | P08581 | 1/20 | 0.56 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.56 |
| ▸ | PIM1 | P11309 | 1/20 | 0.56 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.56 |
| ▸ | CDK8 | P49336 | 1/20 | 0.56 |
| ▸ | PRKX | P51817 | 1/20 | 0.56 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.56 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.56 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2264595 | 0.85 | RAB9A (0.62) | MTORRAB9AMEN1KMT2ANPC1 | |
| SCHEMBL27193042 | 0.81 | RAB9A (0.79) | MTORRAB9AMEN1KMT2ANPC1 | |
| SCHEMBL30851500 | 0.81 | RAB9A (0.79) | MTORRAB9AMEN1KMT2ANPC1 | |
| SCHEMBL2267263 | 0.81 | CA12 (0.57) | MTORRAB9AMEN1KMT2ANPC1 | |
| SCHEMBL4555389 | 0.80 | KMT2A (0.72) | MTORRAB9AMEN1KMT2ANPC1 | |
| SCHEMBL24272323 | 0.79 | MTOR (0.69) | MTORRAB9AMEN1KMT2ANPC1 | |
| SCHEMBL2817252 | 0.78 | SMN1; SMN2 (0.68) | RAB9AMEN1KMT2ANPC1MAPT | |
| SCHEMBL4113845 | 0.77 | RAB9A (0.68) | MTORRAB9AMEN1KMT2ANPC1 | |
| SCHEMBL12218440 | 0.77 | RAB9A (0.79) | MTORRAB9AMEN1KMT2ANPC1 | |
| SCHEMBL4454606 | 0.77 | RAB9A (0.68) | MTORRAB9AMEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1874317-A2 | PREPARATION AND USE OF ARYL ALKYL ACID DERIVATIVES FOR THE TREATMENT OF OBESITY | Bayer Pharmaceuticals Corporation (US) | 2008-01-09 | — | — | EP | claimed |
| WO-2006113919-A2 | ARYL ALKYL ACID DERIVATIVES FOR AND USE THEREOF | BAYER PHARMACEUTICALS CORPORATION (US) | 2006-10-26 | — | — | WO | claimed |