⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12712009 | 0.83 | — | — | |
| SCHEMBL179561 | 0.80 | — | — | |
| SCHEMBL3293803 | 0.78 | LMNA (0.38) | — | |
| Hydrochloric Acid SCHEMBL29184596 | 0.78 | LMNA (0.32) | — | |
| Hydrochloric Acid SCHEMBL28368426 | 0.78 | LMNA (0.32) | — | |
| SCHEMBL19526005 | 0.78 | — | — | |
| SCHEMBL1933286 | 0.78 | — | — | |
| SCHEMBL574414 | 0.77 | GGT1 (0.54) | — | |
| SCHEMBL159588 | 0.77 | GGT1 (0.54) | — | |
| SCHEMBL164555 | 0.77 | GGT1 (0.54) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1206228-C | N-heterocyclic derivatives as NOS inhibitors | BERLEX LAB (US) | 2005-06-15 | — | — | CN | claimed |
| CN-1382136-A | N-heterocyclic derivatives as NOS inhibitors | BERLEX LAB (US) | 2002-11-27 | — | — | CN | claimed |
| US-20240016942-A1 | STAT DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. | 2024-01-18 | — | — | US | disclosed |
| US-20240016942-A1 | STAT DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. | 2024-01-18 | — | — | US | disclosed |
| US-20240016942-A1 | STAT DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. | 2024-01-18 | — | — | US | disclosed |
| CN-115776891-A | STAT degradants and uses thereof | 凯麦拉医疗公司 | 2023-03-10 | — | — | CN | disclosed |
| EP-4121055-A1 | STAT DEGRADERS AND USES THEREOF | Kymera Therapeutics, Inc. (US) | 2023-01-25 | — | — | EP | disclosed |
| WO-2021188696-A1 | STAT DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2021-09-23 | — | — | WO | disclosed |
| WO-2021188696-A1 | STAT DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2021-09-23 | — | — | WO | disclosed |
| US-7345180-B2 | Compound inhibiting dipeptidyl peptidase IV | SANWA KAGAKU KENKYUSHO CO., LTD. (JP) | 2008-03-18 | — | — | US | disclosed |
| US-20060229286-A1 | Compound inhibiting dipeptidyl peptidase IV | SANWA KAGAKU KENKYUSHO CO., LTD. (JP) | 2006-10-12 | — | — | US | disclosed |
| EP-1595866-A1 | COMPOUND INHIBITING DIPEPTIDYL PEPTIDASE IV | Sanwa Kagaku Kenkyusho Co., Ltd. (JP) | 2005-11-16 | — | — | EP | disclosed |
| CN-1206228-C | N-heterocyclic derivatives as NOS inhibitors | BERLEX LAB (US) | 2005-06-15 | — | — | CN | disclosed |
| JP-2003231670-A | METHOD FOR PRODUCING AMINO ACID AMIDE | MITSUBISHI RAYON CO LTD | 2003-08-19 | — | — | JP | disclosed |
| CN-1382136-A | N-heterocyclic derivatives as NOS inhibitors | BERLEX LAB (US) | 2002-11-27 | — | — | CN | disclosed |
| EP-0812311-A1 | HIGHLY POLYMERIZABLE N-VINYLCARBOXYLIC ACID AMIDE AND PRODUCTION PROCESS THEREOF | SHOWA DENKO KABUSHIKI KAISHA (JP) | 1997-12-17 | — | — | EP | disclosed |
| WO-1997024315-A1 | HIGHLY POLYMERIZABLE N-VINYLCARBOXYLIC ACID AMIDE AND PRODUCTION PROCESS THEREOF | SHOWA DENKO K.K. (JP) | 1997-07-10 | — | — | WO | disclosed |
| EP-0104888-B1 | PROCESS FOR PREPARING 2-HYDROXY-2-PHENYLETHYLAMINES | ELI LILLY AND COMPANY (US) | 1986-10-15 | — | — | EP | disclosed |
| EP-0104888-A1 | Process for preparing 2-hydroxy-2-phenylethylamines | ELI LILLY AND COMPANY (US) | 1984-04-04 | — | — | EP | disclosed |