Sugi Predict

Sugi Predict / Compounds / SCHEMBL5069435

SCHEMBL5069435

SCHEMBL5069435

C=Cc1ccc2c(c1)N(C)c1ccccc1N2C

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 3/20 0.47
▸ MAPT P10636 1/20 0.47
▸ PKM P14618 1/20 0.47
▸ TP53 P04637 1/20 0.42
▸ TDP1 Q9NUW8 1/20 0.42
▸ TSHR P16473 1/20 0.41
▸ MAOA P21397 1/20 0.39
▸ NOX1 Q9Y5S8 3/20 0.37
▸ SLC6A2 P23975 2/20 0.37
▸ SLC6A4 P31645 2/20 0.37
▸ MEN1 O00255 1/20 0.37
▸ ADRA2A P08913 1/20 0.37
▸ ADRA2B P18089 1/20 0.37
▸ ADRA2C P18825 1/20 0.37
▸ CHRM3 P20309 1/20 0.37
▸ HTR2C P28335 1/20 0.37
▸ DRD3 P35462 1/20 0.37
▸ HTR2B P41595 1/20 0.37
▸ KMT2A Q03164 1/20 0.37
▸ L3MBTL1 Q9Y468 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30708498 1.00 ALDH1A1 (0.47) ALDH1A1MAPTPKMTP53TDP1
SCHEMBL11592363 0.81 MAOA (0.61) ALDH1A1MAPTPKMTDP1MAOA
SCHEMBL30419778 0.81 MAOA (0.61) ALDH1A1MAPTPKMTDP1MAOA
SCHEMBL25841832 0.81 ALDH1A1 (0.43) ALDH1A1MAPTPKMTP53TDP1
SCHEMBL31389019 0.78 MAPT (0.64) ALDH1A1MAPTPKMTDP1MAOA
SCHEMBL25841708 0.78 MAOA (0.53) ALDH1A1MAPTPKMTP53MAOA
SCHEMBL25841774 0.78 ALDH1A1 (0.38) ALDH1A1MAPTPKMTP53TDP1
SCHEMBL27924965 0.76 ALDH1A1 (0.57) ALDH1A1MAPTPKMTP53TDP1
SCHEMBL28718754 0.74 MAPT (0.46) ALDH1A1MAPTTP53TSHRSLC6A2
SCHEMBL13636983 0.74 — —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113801255-B 5,10-dialkyl-5,10-dihydrophenazine polymer, preparation method and application thereof 中国科学院上海有机化学研究所 2022-11-22 — — CN claimed
CN-113801255-A 5, 10-dialkyl-5, 10-dihydrophenazine polymer, preparation method and application thereof 中国科学院上海有机化学研究所 2021-12-17 — — CN claimed
US-7450293-B2 Electrochromic salts, solutions, and devices LOS ALAMOS NATIONAL SECURITY, LLC (US) 2008-11-11 — — US claimed
US-7436570-B2 Electrochromic salts, solutions, and devices LOS ALAMOS NATIONAL SECURITY, LLC (US) 2008-10-14 — — US claimed
EP-1457813-B1 An improved electrochromic medium capable of producing a pre-selected color GENTEX CORP (US) 2007-01-24 — — EP claimed
US-20050151467-A1 Electrochromic salts, solutions, and devices TRIAD NATIONAL SECURITY, LLC 2005-07-14 — — US claimed
US-20050116627-A1 Electrochromic salts, solutions, and devices TRIAD NATIONAL SECURITY, LLC 2005-06-02 — — US claimed
EP-1457813-A2 An improved electrochromic medium capable of producing a pre-selected color Gentex Corporation (US) 2004-09-15 — — EP claimed
EP-0972227-B1 AN IMPROVED ELECTROCHROMIC MEDIUM CAPABLE OF PRODUCING A PRE-SELECTED COLOR GENTEX CORP (US) 2004-07-14 — — EP claimed
WO-2004000800-A2 ELECTROCHROMIC SALTS, SOLUTIONS, AND DEVICES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2003-12-31 — — WO claimed
US-20030234379-A1 Electrochromic salts, solutions, and devices LOS ALAMOS NATIONAL SECURITY, LLC 2003-12-25 — — US claimed
US-6020987-A Electrochromic medium capable of producing a pre-selected color GENTEX CORPORATION (US) 2000-02-01 — — US claimed
US-5998617-A MIXTURE OF ELECTROACTIVE MATERIALS AT PRESELECTIVE CONCENTRATION; GRAY COLOR GENTEX CORPORATION (US) 1999-12-07 — — US claimed
CN-113801255-B 5,10-dialkyl-5,10-dihydrophenazine polymer, preparation method and application thereof 中国科学院上海有机化学研究所 2022-11-22 — — CN disclosed
CN-113801255-A 5, 10-dialkyl-5, 10-dihydrophenazine polymer, preparation method and application thereof 中国科学院上海有机化学研究所 2021-12-17 — — CN disclosed
EP-3221420-B1 PHOTOCHROMIC-ELECTROCHROMIC COMPOSITIONS SWITCH MAT INC (CA) 2021-02-17 — — EP disclosed
US-6141137-A Electrochromic media for producing a preselected color GENTEX CORPORATION (US) 2000-10-31 — — US disclosed
US-6037471-A FOR ELECTROCHROMIC MIRRORS FOR MOTOR VEHICLES GENTEX CORPORATION (US) 2000-03-14 — — US disclosed
US-6020987-A Electrochromic medium capable of producing a pre-selected color GENTEX CORPORATION (US) 2000-02-01 — — US disclosed
US-5998617-A MIXTURE OF ELECTROACTIVE MATERIALS AT PRESELECTIVE CONCENTRATION; GRAY COLOR GENTEX CORPORATION (US) 1999-12-07 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050151467-A1 Electrochromic salts, solutions, and devices F8, ETV6, HCN4 ALDH1A1 4195/4885MAPT 2765/4885PKM 2126/4885
US-20050116627-A1 Electrochromic salts, solutions, and devices F8, ETV6, HCN4 ALDH1A1 4195/4885MAPT 2765/4885PKM 2126/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.