Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 5/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 4/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | AXL | P30530 | 1/20 | 0.32 |
| ▸ | MERTK | Q12866 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3902420 | 1.00 | REN (0.38) | RENTHRBALDH1A1CYP3A4CYP2D6 | |
| SCHEMBL1036492 | 0.94 | REN (0.37) | RENTHRBALDH1A1CYP3A4CYP2D6 | |
| SCHEMBL3912017 | 0.94 | REN (0.37) | RENTHRBALDH1A1CYP3A4CYP2D6 | |
| SCHEMBL1038488 | 0.91 | BCL9 (0.36) | RENTHRBTP53AXLMERTK | |
| SCHEMBL1039229 | 0.91 | REN (0.38) | RENTHRBALDH1A1CYP3A4CYP2D6 | |
| SCHEMBL3910212 | 0.90 | THRB (0.35) | RENTHRBALDH1A1CYP3A4CYP2D6 | |
| SCHEMBL1038926 | 0.90 | REN (0.35) | RENTHRBALDH1A1CYP3A4CYP2D6 | |
| SCHEMBL1035197 | 0.90 | REN (0.38) | RENTHRBALDH1A1CYP3A4CYP2D6 | |
| SCHEMBL3902895 | 0.90 | REN (0.35) | RENTHRBALDH1A1CYP3A4CYP2D6 | |
| SCHEMBL3945444 | 0.90 | REN (0.35) | RENTHRBALDH1A1CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1973903-A1 | SUBSTITUTED 4-PHENYLPIPERIDINES | Speedel Experimenta AG (CH) | 2008-10-01 | — | — | EP | disclosed |
| WO-2007082907-A1 | SUBSTITUTED 4-PHENYLPIPERIDINES | SPEEDEL EXPERIMENTA AG (CH) | 2007-07-26 | — | — | WO | disclosed |