Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.37 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.35 |
| ▸ | MPO | P05164 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5069854 | 1.00 | HTR2A (0.38) | HTR2AHTTSMN1; SMN2SLC6A2NPC1 | |
| SCHEMBL5069973 | 0.84 | MPO (0.54) | SMN1; SMN2NPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL5069975 | 0.84 | MPO (0.54) | SMN1; SMN2NPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL4128789 | 0.84 | ALDH1A1 (0.39) | HTR2AHTTSMN1; SMN2SLC6A2NPC1 | |
| SCHEMBL4128786 | 0.84 | SMN1; SMN2 (0.41) | HTR2ASMN1; SMN2ALDH1A1LMNAKMT2A | |
| SCHEMBL6600791 | 0.82 | FOLH1 (0.56) | HTR2AHTTSLC6A2FOLH1ALDH1A1 | |
| SCHEMBL11525175 | 0.79 | FOLH1 (0.53) | HTR2AHTTSLC6A2FOLH1ALDH1A1 | |
| SCHEMBL11585501 | 0.78 | BID (0.48) | — | |
| SCHEMBL11585499 | 0.78 | BID (0.48) | — | |
| SCHEMBL4109998 | 0.77 | HMGB1 (0.50) | HTR2AFOLH1CTBP2ALDH1A1TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1985615-A1 | METHOD FOR PRODUCING BENZAZEPINONE | API Corporation (JP) | 2008-10-29 | — | — | EP | disclosed |