Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ARG1 | P05089 | 2/20 | 0.36 |
| ▸ | ARG2 | P78540 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | TLR4 | O00206 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.31 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5069946 | 0.90 | TLR4 (0.42) | ARG1ARG2CYP2C9ALDH1A1MAPT | |
| SCHEMBL1508100 | 0.89 | MAPT (0.44) | ARG1ARG2CYP2C9ALDH1A1MAPT | |
| SCHEMBL2576207 | 0.87 | TP53 (0.40) | CYP2C9MAPTKMT2A | |
| SCHEMBL10450411 | 0.86 | TP53 (0.43) | CYP2C9ALDH1A1MAPTKMT2A | |
| SCHEMBL10471196 | 0.86 | TP53 (0.43) | CYP2C9ALDH1A1MAPTKMT2A | |
| SCHEMBL5478105 | 0.86 | TP53 (0.43) | CYP2C9ALDH1A1MAPTKMT2A | |
| SCHEMBL11310025 | 0.84 | POLB (0.39) | ARG1ARG2ALDH1A1 | |
| SCHEMBL10902327 | 0.83 | MAPT (0.43) | ARG1ARG2CYP2C9MAPTTLR4 | |
| SCHEMBL9627093 | 0.78 | FFAR3 (0.50) | ARG1ARG2CYP2C9ALDH1A1MAPT | |
| SCHEMBL11129926 | 0.76 | LMNA (0.47) | ARG1ARG2CYP2C9LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8389073-B2 | Four-ring liquid crystal compound having tetrahydropyran and 2,2′,3,3′-tetrafluorobiphenyl, liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2013-03-05 | — | — | US | disclosed |
| US-20110297881-A1 | FOUR-RING LIQUID CRYSTAL COMPOUND HAVING TETRAHYDROPYRAN AND 2,2',3,3'-TETRAFLUOROBIPHENYL, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE | CHISSO PETROCHEMICAL CORPORATION (JP) | 2011-12-08 | — | — | US | disclosed |
| US-6174573-B1 | 3,4'-(HALO OR HALOGEN),4-((CYCLO)ALK(OXY)CARBONYLOXY)-DIPHENYLACETYLENE COMPOUNDS WHICH INCREASE THE N-I POINT (NEMATIC ANISOTROPY PHASE TRANSITION TEMPERATURE), AND THE DOUBLE REFRACTIVE INDEX | CITIZEN WATCH CO., LTD. (JP) | 2001-01-16 | — | — | US | disclosed |
| US-5972244-A | INCREASE THE N-I POINT, DECREASE VISCOSITY, AND INCREASE DOUBLE REFRACTIVE INDEX OF A LIQUID CRYSTAL COMPOSITION WITHOUT AFFECTING THRESHOLD VOLTAGE | CITIZEN WATCH CO., LTD. (JP) | 1999-10-26 | — | — | US | disclosed |
| US-5482652-A | CYCLOHEXANECARBOXYLIC ESTERS WITH PYRIMIDINE COMPOUNDS | CANON KABUSHIKI KAISHA (JP) | 1996-01-09 | — | — | US | disclosed |
| US-5389296-A | High speed responsiveness to an electric field and less temperature dependancy; ferroelectric chiral sematic; contains a mesomorphic compound | CANON KABUSHIKI KAISHA (JP) | 1995-02-14 | — | — | US | disclosed |
| US-5348677-A | Electro-optical liquid crystal display element | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1994-09-20 | — | — | US | disclosed |
| EP-0293910-B1 | Liquid crystal composition and liquid crystal device containing same | CANON KK (JP) | 1994-02-02 | — | — | EP | disclosed |
| US-5196140-A | ELECTRO-OPTICAL LIQUID CRYSTAL DISPLAY ELEMENT | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1993-03-23 | — | — | US | disclosed |
| US-5139697-A | Smaller temperature dependence of response speed | CANON KABUSHIKI KAISHA (JP) | 1992-08-18 | — | — | US | disclosed |
| US-5073306-A | Trifluoromethylalkyl substituted | CANON KABUSHIKI KAISHA (JP) | 1991-12-17 | — | — | US | disclosed |
| US-4985583-A | Liquid Crystals | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1991-01-15 | — | — | US | disclosed |
| US-4918213-A | HAVING A TRIFLUOROMETHYL GROUP ATTACHED TO ASYMMETRIC CARBON ATOM; STABLE; OPTICAL DEVICES | CANON KABUSHIKI KAISHA (JP) | 1990-04-17 | — | — | US | disclosed |
| US-4816179-A | LIQUID CRYSTAL DIELECTRICS OF AROMATIC ESTERS | CHISSO CORPORATION (JP) | 1989-03-28 | — | — | US | disclosed |
| EP-0301511-A1 | Optically active compound and liquid crystal composition containing same | CANON KABUSHIKI KAISHA (JP) | 1989-02-01 | — | — | EP | disclosed |
| EP-0293910-A2 | Liquid crystal composition and liquid crystal device containing same | CANON KABUSHIKI KAISHA (JP) | 1988-12-07 | — | — | EP | disclosed |
| US-4713197-A | Nitrogen-containing heterocyclic compounds | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1987-12-15 | — | — | US | disclosed |
| US-4683078-A | LIQUID CRYSTAL DIELECTRICS | CHISSO CORPORATION (JP) | 1987-07-28 | — | — | US | disclosed |
| US-4673529-A | LIQUID CRYSTALS JLMOKOUM INTEGRATED CIRCUITS | CHISSO CORPORATION (JP) | 1987-06-16 | — | — | US | disclosed |
| US-4290905-A | FOR LIQUID CRYSTAL DISPLAYS | KABUSHIKI KAISHA SUWA SEIKOSHA (JP) | 1981-09-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110297881-A1 | FOUR-RING LIQUID CRYSTAL COMPOUND HAVING TETRAHYDROPYRAN AND 2,2',3,3'-TETRAFLUOROBIPHENYL, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE | CCT4, TEC, TCF4 | ARG1 4780/4885ARG2 4875/4885CYP2C9 343/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.