SCHEMBL5070055

SCHEMBL5070055

CCN1c2ccc(C(F)(F)F)cc2N(CC)c2cc(C)c(C)cc21

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.40
ALDH1A1 P00352 3/20 0.40
NPSR1 Q6W5P4 3/20 0.40
HPGD P15428 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
XBP1 P17861 1/20 0.38
PKM P14618 1/20 0.38
HSP90AA1 P07900 1/20 0.37
GAA P10253 1/20 0.37
PDE2A O00408 2/20 0.35
TSHR P16473 2/20 0.35
LMNA P02545 2/20 0.35
NOTUM Q6P988 1/20 0.35
HTR2A P28223 1/20 0.35
HTR2C P28335 1/20 0.35
HTR2B P41595 1/20 0.35
TP53 P04637 2/20 0.35
NPC1 O15118 1/20 0.35
ABCB11 O95342 1/20 0.35
CYP1A2 P05177 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5157971 0.88 ALDH1A1 (0.36) MAPTALDH1A1NPSR1HPGDSMN1; SMN2
SCHEMBL5140612 0.80 MAPT (0.37) MAPTALDH1A1NPSR1HPGDSMN1; SMN2
SCHEMBL17353592 0.77 TP53 (0.47) MAPTALDH1A1NPSR1HPGDSMN1; SMN2
SCHEMBL29865250 0.77 TP53 (0.47) MAPTALDH1A1NPSR1HPGDSMN1; SMN2
SCHEMBL5070034 0.77 ALDH1A1 (0.41) MAPTALDH1A1NPSR1HPGDSMN1; SMN2
SCHEMBL17356867 0.74 MAPK1 (0.42) MAPTALDH1A1NPSR1SMN1; SMN2XBP1
SCHEMBL21445198 0.70 TP53 (0.67) MAPTALDH1A1NPSR1HPGDSMN1; SMN2
SCHEMBL1755260 0.70 PDE2A (0.46) MAPTALDH1A1PDE2ATSHRNOTUM
SCHEMBL12428655 0.69 GALR3 (0.39) MAPTGAATSHRLMNATP53
SCHEMBL1573651 0.68 ALDH1A1 (0.37) MAPTALDH1A1NPSR1XBP1PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7436570-B2 Electrochromic salts, solutions, and devices LOS ALAMOS NATIONAL SECURITY, LLC (US) 2008-10-14 US claimed
EP-1457813-B1 An improved electrochromic medium capable of producing a pre-selected color GENTEX CORP (US) 2007-01-24 EP claimed
US-20050116627-A1 Electrochromic salts, solutions, and devices TRIAD NATIONAL SECURITY, LLC 2005-06-02 US claimed
EP-1457813-A2 An improved electrochromic medium capable of producing a pre-selected color Gentex Corporation (US) 2004-09-15 EP claimed
EP-0972227-B1 AN IMPROVED ELECTROCHROMIC MEDIUM CAPABLE OF PRODUCING A PRE-SELECTED COLOR GENTEX CORP (US) 2004-07-14 EP claimed
US-6020987-A Electrochromic medium capable of producing a pre-selected color GENTEX CORPORATION (US) 2000-02-01 US claimed
US-5998617-A MIXTURE OF ELECTROACTIVE MATERIALS AT PRESELECTIVE CONCENTRATION; GRAY COLOR GENTEX CORPORATION (US) 1999-12-07 US claimed
EP-3221420-B1 PHOTOCHROMIC-ELECTROCHROMIC COMPOSITIONS SWITCH MAT INC (CA) 2021-02-17 EP disclosed
US-10647913-B2 Photochromic-electrochromic compositions SWITCH MATERIALS INC. (CA) 2020-05-12 US disclosed
US-20170355901-A1 PHOTOCHROMIC-ELECTROCHROMIC COMPOSITIONS SOLUTIA CANADA INC. (CA) 2017-12-14 US disclosed
EP-3221420-A1 PHOTOCHROMIC-ELECTROCHROMIC COMPOSITIONS Switch Materials, Inc. (CA) 2017-09-27 EP disclosed
WO-2016077918-A1 PHOTOCHROMIC-ELECTROCHROMIC COMPOSITIONS SWITCH MATERIALS INC. (CA) 2016-05-26 WO disclosed
US-7436570-B2 Electrochromic salts, solutions, and devices LOS ALAMOS NATIONAL SECURITY, LLC (US) 2008-10-14 US disclosed
EP-1457813-A2 An improved electrochromic medium capable of producing a pre-selected color Gentex Corporation (US) 2004-09-15 EP disclosed
EP-0972227-B1 AN IMPROVED ELECTROCHROMIC MEDIUM CAPABLE OF PRODUCING A PRE-SELECTED COLOR GENTEX CORP (US) 2004-07-14 EP disclosed
US-6037471-A FOR ELECTROCHROMIC MIRRORS FOR MOTOR VEHICLES GENTEX CORPORATION (US) 2000-03-14 US disclosed
US-6020987-A Electrochromic medium capable of producing a pre-selected color GENTEX CORPORATION (US) 2000-02-01 US disclosed
EP-0972227-A1 AN IMPROVED ELECTROCHROMIC MEDIUM CAPABLE OF PRODUCING A PRE-SELECTED COLOR GENTEX CORPORATION (US) 2000-01-19 EP disclosed
US-5998617-A MIXTURE OF ELECTROACTIVE MATERIALS AT PRESELECTIVE CONCENTRATION; GRAY COLOR GENTEX CORPORATION (US) 1999-12-07 US disclosed
WO-1998044384-A1 AN IMPROVED ELECTROCHROMIC MEDIUM CAPABLE OF PRODUCING A PRE-SELECTED COLOR GENTEX CORPORATION (US) 1998-10-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050116627-A1 Electrochromic salts, solutions, and devices F8, ETV6, HCN4 MAPT 2765/4885ALDH1A1 4195/4885NPSR1 4115/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.