Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GALR3 | O60755 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CCR3 | P51677 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | ACKR3 | P25106 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.36 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.36 |
| ▸ | UBE2M | P61081 | 1/20 | 0.36 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.36 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.36 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.36 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.36 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL401833 | 0.85 | TP53 (0.43) | GALR3RAB9ACCR3TP53ACKR3 | |
| SCHEMBL402389 | 0.85 | RAB9A (0.43) | GALR3RAB9ACCR3TP53ACKR3 | |
| SCHEMBL402362 | 0.84 | RAB9A (0.40) | GALR3RAB9ACCR3TP53ACKR3 | |
| SCHEMBL398774 | 0.84 | ALDH1A1 (0.44) | GALR3RAB9ACCR3TP53ACKR3 | |
| SCHEMBL402769 | 0.84 | ALDH1A1 (0.44) | GALR3RAB9ACCR3TP53ACKR3 | |
| SCHEMBL398834 | 0.84 | KCNH2 (0.43) | GALR3RAB9ACCR3TP53ACKR3 | |
| SCHEMBL401209 | 0.84 | RAB9A (0.44) | GALR3RAB9ACCR3TP53ACKR3 | |
| SCHEMBL545115 | 0.84 | KCNH2 (0.45) | GALR3RAB9ACCR3ACKR3THRB | |
| SCHEMBL402434 | 0.83 | GALR3 (0.45) | GALR3RAB9ACCR3TP53ACKR3 | |
| SCHEMBL401419 | 0.82 | GALR3 (0.41) | GALR3RAB9ACCR3TP53ACKR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1959960-A2 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS AND METHODS | Cytokinetics, Inc. (US) | 2008-08-27 | — | — | EP | disclosed |
| WO-2007070683-A2 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS AND METHODS | CYTOKINETICS, INC. (US) | 2007-06-21 | — | — | WO | disclosed |