Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30497904 | 0.96 | TSHR (0.36) | TSHRTHRB | |
| SCHEMBL5068520 | 0.95 | TSHR (0.37) | TSHRTHRB | |
| SCHEMBL195549 | 0.92 | TSHR (0.45) | TSHRTHRBALDH1A1 | |
| SCHEMBL30497903 | 0.90 | TSHR (0.39) | TSHRTHRB | |
| SCHEMBL5070641 | 0.89 | TSHR (0.38) | TSHRTHRB | |
| SCHEMBL5068522 | 0.88 | TSHR (0.37) | TSHRTHRB | |
| SCHEMBL5692365 | 0.87 | TSHR (0.42) | TSHRTHRBALDH1A1 | |
| SCHEMBL517397 | 0.87 | TSHR (0.42) | TSHRTHRBALDH1A1 | |
| SCHEMBL711930 | 0.87 | TSHR (0.42) | TSHRTHRBALDH1A1 | |
| SCHEMBL155309 | 0.87 | THRB (0.43) | TSHRTHRBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1928979-A1 | FUNCTIONALIZED PHOTOREACTIVE COMPOUNDS | Rolic AG (CH) | 2008-06-11 | — | — | EP | disclosed |
| WO-2007033506-A1 | FUNCTIONALIZED PHOTOREACTIVE COMPOUNDS | ROLIC AG (CH) | 2007-03-29 | — | — | WO | disclosed |