SCHEMBL5070769

SCHEMBL5070769

C=COC(=O)C1(C)CC2C=CC1C2

nearest known ligand 0.36

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
P2RX7 Q99572 1/20 0.36
CYP2D6 P10635 1/20 0.33
CYP2C19 P33261 1/20 0.33
CETP P11597 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethylene SCHEMBL20471720 0.81 P2RX7 (0.40) P2RX7CYP2D6CYP2C19CETP
SCHEMBL5066632 0.81 P2RX7 (0.34) P2RX7CYP2D6CYP2C19CETP
SCHEMBL200115 0.80 P2RX7 (0.41) P2RX7CYP2D6CYP2C19CETP
SCHEMBL18938394 0.80 P2RX7 (0.41) P2RX7CYP2D6CYP2C19CETP
SCHEMBL16001616 0.78 P2RX7 (0.36) P2RX7CYP2D6CYP2C19CETP
SCHEMBL200228 0.76 CYP2C19 (0.40) P2RX7CYP2D6CYP2C19CETP
SCHEMBL3367328 0.76 P2RX7 (0.37) P2RX7CYP2D6CYP2C19CETP
SCHEMBL5456663 0.76 P2RX7 (0.39) P2RX7CYP2D6CYP2C19CETP
SCHEMBL1451420 0.76 P2RX7 (0.37) P2RX7CYP2D6CYP2C19CETP
SCHEMBL5184481 0.76 P2RX7 (0.37) P2RX7CYP2D6CYP2C19CETP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1655321-B1 POLYMERIZABLE COMPOSITIONS AND MOLDED ARTICLES PRODUCED BY USING THE SAME ZEON CORP (JP) 2012-11-21 EP disclosed
US-7381782-B2 Polymerizable composition and molded articles produced by using the same ZEON CORPORATION (JP) 2008-06-03 US disclosed
US-20060258828-A1 Polymerizable composition and molded articles produced by using the same ZEON CORPORATION (JP) 2006-11-16 US disclosed
EP-1655321-A1 POLYMERIZABLE COMPOSITIONS AND MOLDED ARTICLES PRODUCED BY USING THE SAME Zeon Corporation (JP) 2006-05-10 EP disclosed