SCHEMBL200228

SCHEMBL200228

CCOC(=O)C1(C)CC2C=CC1C2

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 2/20 0.40
CYP2D6 P10635 1/20 0.40
P2RX7 Q99572 1/20 0.37
CETP P11597 1/20 0.35
F10 P00742 2/20 0.34
OPRM1 P35372 1/20 0.33
LMNA P02545 1/20 0.33
BRD4 O60885 1/20 0.31
POLB P06746 1/20 0.31
ADAM17 P78536 1/20 0.31
MAPK1 P28482 1/20 0.31
SLC22A1 O15245 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
GRM1 Q13255 1/20 0.30
BLM P54132 1/20 0.30
PMP22 Q01453 1/20 0.30
KDM4E B2RXH2 1/20 0.30
CYP1A2 P05177 1/20 0.30
CYP3A4 P08684 1/20 0.30
CYP2C9 P11712 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25428359 0.94 CYP2D6 (0.36) CYP2C19CYP2D6P2RX7CETPF10
SCHEMBL201163 0.88 CYP2D6 (0.38) CYP2C19CYP2D6P2RX7CETP
SCHEMBL200578 0.85 CYP2C19 (0.36) CYP2C19CYP2D6P2RX7CETPLMNA
SCHEMBL21593923 0.84 P2RX7 (0.36) CYP2C19CYP2D6P2RX7CETP
SCHEMBL14628487 0.84 P2RX7 (0.36) CYP2C19CYP2D6P2RX7CETP
SCHEMBL4253408 0.84 P2RX7 (0.36) CYP2C19CYP2D6P2RX7CETP
SCHEMBL32689139 0.84 EPHX2 (0.38) CYP2C19CYP2D6P2RX7LMNAMAPK1
SCHEMBL1451060 0.83 CETP (0.37) CYP2C19CYP2D6P2RX7CETPTSHR
SCHEMBL21593883 0.83 CETP (0.35) CYP2C19CYP2D6P2RX7CETP
SCHEMBL5347783 0.83 P2RX7 (0.35) CYP2C19CYP2D6P2RX7CETP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 444 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117756986-A Cycloolefin copolymer, preparation method thereof, cycloolefin copolymer hydride and optical material 杭州睿丰融创科技有限公司 2024-03-26 CN claimed
US-20040086987-A1 Compound as cholinesterase inhibitor and its isolation from fungus sporotrichum species COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2004-05-06 US claimed
US-20030216473-A1 COMPOUND AS CHOLINESTERASE INHIBITOR AND ITS ISOLATION FROM FUNGUS SPOROTRICHUM SPECIES COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2003-11-20 US claimed
US-4176220-A COORDINATION CATALYST JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1979-11-27 US claimed
EP-4737515-A1 RUBBER COMPOSITION FOR TIRES, AND TIRE BRIDGESTONE CORPORATION (JP) 2026-05-06 EP disclosed
EP-4737517-A1 RUBBER COMPOSITION FOR TIRE, AND TIRE BRIDGESTONE CORPORATION (JP) 2026-05-06 EP disclosed
EP-4737516-A1 RUBBER COMPOSITION FOR TIRES, AND TIRE BRIDGESTONE CORPORATION (JP) 2026-05-06 EP disclosed
EP-4737513-A1 RUBBER COMPOSITION FOR TIRE, AND TIRE BRIDGESTONE CORPORATION (JP) 2026-05-06 EP disclosed
US-20260078079-A1 FRAGRANCE AND FLAVOR COMPOSITIONS COMPRISING NORBORNANE AND NORBORNENE DERIVATIVES OSMO LABS PBC (US) 2026-03-19 US disclosed
US-20260045492-A1 COMPOSITE PARTICLES AND METHOD OF PRODUCING SAME, ELECTRODE FOR ELECTROCHEMICAL DEVICE, AND ELECTROCHEMICAL DEVICE ZEON CORPORATION (JP) 2026-02-12 US disclosed
EP-4693451-A1 COMPOSITE PARTICLES Zeon Corporation (JP) 2026-02-11 EP disclosed
EP-4678367-A1 METHOD FOR MANUFACTURING ALICYCLIC STRUCTURE-CONTAINING POLYMER RECYCLED PRODUCT Zeon Corporation (JP) 2026-01-14 EP disclosed
EP-1025989-A1 COMPOSITE FILM NIPPON ZEON CO., LTD. (JP) 2000-08-09 EP disclosed
EP-0995784-A1 ADHESIVE FOR SEMICONDUCTOR COMPONENTS NIPPON ZEON CO., LTD. (JP) 2000-04-26 EP disclosed
WO-2000020472-A1 CATALYST AND METHODS FOR POLYMERIZING CYCLOOLEFINS THE B.F. GOODRICH COMPANY (US) 2000-04-13 WO disclosed
EP-0987719-A1 INSULATING MATERIALS CONTAINING CYCLOOLEFINIC POLYMERS NIPPON ZEON CO., LTD. (JP) 2000-03-22 EP disclosed
EP-0931816-A1 NORBORNENE POLYMER COMPOSITION NIPPON ZEON CO., LTD. (JP) 1999-07-28 EP disclosed
EP-0930541-A1 Radiation sensitive resin composition JSR Corporation (JP) 1999-07-21 EP disclosed
EP-0789278-A2 Radiation-sensitive resin composition JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1997-08-13 EP disclosed
US-4329270-A POLYNORBORNENE DIRIVATIVES EASTMAN KODAK COMPANY (US) 1982-05-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030216473-A1 COMPOUND AS CHOLINESTERASE INHIBITOR AND ITS ISOLATION FROM FUNGUS SPOROTRICHUM SPECIES CYP51A1, ACHE, BCHE CYP2C19 515/4885CYP2D6 587/4885P2RX7 2191/4885
US-20260045492-A1 COMPOSITE PARTICLES AND METHOD OF PRODUCING SAME, ELECTRODE FOR ELECTROCHEMICAL DEVICE, AND ELECTROCHEMICAL DEVICE CACNA2D1, CACNA2D2, CACNA2D4 CYP2C19 1326/4885CYP2D6 4382/4885P2RX7 1969/4885
US-20260078079-A1 FRAGRANCE AND FLAVOR COMPOSITIONS COMPRISING NORBORNANE AND NORBORNENE DERIVATIVES CBR1, CBR3, TAS2R1 CYP2C19 1533/4885CYP2D6 650/4885P2RX7 239/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.