Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAMBP | O95630 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL965095 | 0.91 | MAPT (0.48) | STAMBPKMT2AMEN1L3MBTL1GAA | |
| SCHEMBL14735698 | 0.84 | MAPT (0.46) | KMT2AMEN1GAAMAPT | |
| SCHEMBL5146388 | 0.82 | SMPD1 (0.41) | STAMBPKMT2AMEN1L3MBTL1RAB9A | |
| SCHEMBL1509146 | 0.81 | EGLN1 (0.49) | STAMBPKMT2AMEN1L3MBTL1GAA | |
| SCHEMBL8784539 | 0.80 | GAA (0.45) | STAMBPKMT2AMEN1GAARAB9A | |
| SCHEMBL966853 | 0.79 | KMT2A (0.53) | KMT2AMEN1L3MBTL1GAAMAPT | |
| SCHEMBL8786558 | 0.79 | SMPD1 (0.42) | STAMBPKMT2AMEN1GAARAB9A | |
| SCHEMBL1509716 | 0.77 | EGLN1 (0.53) | GAAMAPT | |
| SCHEMBL8883714 | 0.77 | MEN1 (0.50) | KMT2AMEN1GAAMAPT | |
| SCHEMBL8880594 | 0.77 | MEN1 (0.50) | KMT2AMEN1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1893186-A2 | IMPROVED TREATMENT FOR ANEMIA USING A HIF-ALPHA STABILISING AGENT | FIBROGEN, INC. (US) | 2008-03-05 | — | — | EP | disclosed |
| WO-2006133391-A2 | IMPROVED TREATMENT FOR ANEMIA USING A HIF-ALPHA STABILISING AGENT | FIBROGEN, INC. (US) | 2006-12-14 | — | — | WO | disclosed |