Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 2/20 | 0.39 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL966853 | 0.91 | KMT2A (0.53) | MAPTGAAEGLN1MEN1KMT2A | |
| SCHEMBL8882701 | 0.89 | MEN1 (0.50) | MAPTGAAEGLN1MEN1KMT2A | |
| SCHEMBL8883714 | 0.89 | MEN1 (0.50) | MAPTGAAEGLN1MEN1KMT2A | |
| SCHEMBL8880594 | 0.89 | MEN1 (0.50) | MAPTGAAEGLN1MEN1KMT2A | |
| SCHEMBL8881979 | 0.89 | MEN1 (0.50) | MAPTGAAEGLN1MEN1KMT2A | |
| SCHEMBL8882089 | 0.86 | GAA (0.44) | MAPTGAAEGLN1MEN1KMT2A | |
| SCHEMBL965095 | 0.84 | MAPT (0.48) | MAPTGAAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL5070931 | 0.84 | STAMBP (0.44) | MAPTGAAMEN1KMT2A | |
| SCHEMBL1509716 | 0.83 | EGLN1 (0.53) | MAPTGAAEGLN1SMN1; SMN2HPGD | |
| SCHEMBL8807029 | 0.82 | GAA (0.42) | MAPTGAAEGLN1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1463823-B1 | METHODS OF INCREASING ENDOGENOUS ERYTHROPOIETIN (EPO) | FIBROGEN INC (US) | 2013-03-06 | — | — | EP | claimed |