Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | ATM | Q13315 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.58 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | CASP1 | P29466 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 3/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.49 |
| ▸ | MET | P08581 | 4/20 | 0.49 |
| ▸ | DAO | P14920 | 1/20 | 0.49 |
| ▸ | CHKA | P35790 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30586439 | 1.00 | ALDH1A1 (0.58) | ALDH1A1MAPTATMKDM4ETP53 | |
| SCHEMBL29673226 | 1.00 | ALDH1A1 (0.58) | ALDH1A1MAPTATMKDM4ETP53 | |
| Iodide SCHEMBL20524052 | 0.98 | ALDH1A1 (0.56) | ALDH1A1MAPTATMKDM4ETP53 | |
| SCHEMBL2597877 | 0.85 | ALDH1A1 (0.59) | ALDH1A1MAPTATMKDM4ETP53 | |
| SCHEMBL1495700 | 0.85 | ALDH1A1 (0.53) | ALDH1A1MAPTATMKDM4ETP53 | |
| Hydrochloric Acid SCHEMBL20562948 | 0.84 | ALDH1A1 (0.58) | ALDH1A1MAPTATMKDM4ETP53 | |
| SCHEMBL19338490 | 0.81 | NPC1 (0.57) | ALDH1A1MAPTATMKDM4ETP53 | |
| SCHEMBL21169605 | 0.81 | NPC1 (0.57) | ALDH1A1MAPTATMKDM4ETP53 | |
| SCHEMBL2107923 | 0.81 | NPC1 (0.57) | ALDH1A1MAPTATMKDM4ETP53 | |
| SCHEMBL1721002 | 0.81 | NPC1 (0.57) | ALDH1A1MAPTATMKDM4ETP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 246 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116943730-B | Method for preparing cyclic amine compound by catalyzing hydrogenation of pyridine and quinoline compound | 浙江大学 | 2025-04-11 | — | — | CN | claimed |
| CN-116943730-A | Method for preparing cyclic amine compound by catalyzing hydrogenation of pyridine and quinoline compound | 浙江大学 | 2023-10-27 | — | — | CN | claimed |
| EP-0675111-A2 | Process for the preparation of 6-hydroxymethyl-quinolines | BASF AKTIENGESELLSCHAFT (DE) | 1995-10-04 | — | — | EP | claimed |
| US-20250273719-A1 | ION-EXCHANGE MEMBRANE, MEMBRANE ELECTRODE ASSEMBLY, CELL FOR REDOX FLOW BATTERY, AND REDOX FLOW BATTERY | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2025-08-28 | — | — | US | disclosed |
| CN-116943730-B | Method for preparing cyclic amine compound by catalyzing hydrogenation of pyridine and quinoline compound | 浙江大学 | 2025-04-11 | — | — | CN | disclosed |
| US-20250099462-A1 | Certain Triazolopyridines and Triazolopyrazines, Compositions Thereof and Methods of Use Therefor | HUTCHISON MEDIPHARMA LTD (CN) | 2025-03-27 | — | — | US | disclosed |
| EP-4516845-A1 | ION EXCHANGE MEMBRANE, MEMBRANE ELECTRODE ASSEMBLY, CELL FOR REDOX FLOW BATTERIES, AND REDOX FLOW BATTERY | Asahi Kasei Kabushiki Kaisha (JP) | 2025-03-05 | — | — | EP | disclosed |
| WO-2024218632-A1 | ERK PROTEIN KINASE INHIBITORS | ARRAY BIOPHARMA INC. (US) | 2024-10-24 | — | — | WO | disclosed |
| CN-115605477-B | Pyrazolo [1,5-a ] pyridine derivative, preparation method, composition and application thereof | 深圳众格生物科技有限公司 | 2024-07-05 | — | — | CN | disclosed |
| CN-118271197-A | Cyclohexylamine derivative, and composition and application thereof | 上海京新生物医药有限公司 | 2024-07-02 | — | — | CN | disclosed |
| CN-118271234-A | Piperidine derivative, composition and application thereof | 上海京新生物医药有限公司 | 2024-07-02 | — | — | CN | disclosed |
| CN-1237183-A | 6-0-substituted ketolides with antibacterial activity | ABBOTT CO (US) | 1999-12-01 | — | — | CN | disclosed |
| EP-0929563-A1 | 6-O-SUBSTITUTED KETOLIDES HAVING ANTIBACTERIAL ACTIVITY | Abbott Laboratories (US) | 1999-07-21 | — | — | EP | disclosed |
| US-5866549-A | MACROLIDE ANTIBIOTICS | ABBOTT LABORATORIES (US) | 1999-02-02 | — | — | US | disclosed |
| US-5807875-A | OBESITY THERAPY | DR. KARL THOMAE GMBH (DE) | 1998-09-15 | — | — | US | disclosed |
| WO-1998009978-A1 | 6-O-SUBSTITUTED KETOLIDES HAVING ANTIBACTERIAL ACTIVITY | ABBOTT LABORATORIES (US) | 1998-03-12 | — | — | WO | disclosed |
| US-5616620-A | HYPOTENSIVE AGENTS | KARL THOMAE GMBH (DE) | 1997-04-01 | — | — | US | disclosed |
| EP-0675111-A3 | Process for the preparation of 6-hydroxymethyl-quinolines | BASF AKTIENGESELLSCHAFT (DE) | 1995-11-15 | — | — | EP | disclosed |
| EP-0675111-A2 | Process for the preparation of 6-hydroxymethyl-quinolines | BASF AKTIENGESELLSCHAFT (DE) | 1995-10-04 | — | — | EP | disclosed |
| EP-0675111-A2 | Process for the preparation of 6-hydroxymethyl-quinolines | BASF AKTIENGESELLSCHAFT (DE) | 1995-10-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250099462-A1 | Certain Triazolopyridines and Triazolopyrazines, Compositions Thereof and Methods of Use Therefor | KCNJ11, NISCH, CYP4Z1 | ALDH1A1 337/4885MAPT 3267/4885ATM 4256/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.