SCHEMBL5071502

SCHEMBL5071502

C=C(C)C(=O)OCc1c2ccccc2cc2ccccc12.C=C(C)C(=O)OCc1ccc2ccc3cccc4ccc1c2c34

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.42
MEN1 O00255 2/20 0.42
CYP1A2 P05177 2/20 0.40
ERBB2 P04626 1/20 0.40
FYN P06241 1/20 0.40
MAOA P21397 1/20 0.40
ACHE P22303 1/20 0.40
AHR P35869 1/20 0.40
EPHX1 P07099 2/20 0.39
PPARG P37231 1/20 0.37
ALDH1A1 P00352 3/20 0.36
HPGD P15428 3/20 0.36
KDM4E B2RXH2 3/20 0.36
MAPT P10636 2/20 0.36
MTNR1A P48039 1/20 0.34
FAAH O00519 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.33
HSD17B10 Q99714 2/20 0.33
EDNRA P25101 1/20 0.33
TACR1 P25103 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30542093 0.89 KMT2A (0.51) KMT2AMEN1CYP1A2EPHX1PPARG
SCHEMBL417057 0.89 KMT2A (0.51) KMT2AMEN1CYP1A2EPHX1PPARG
SCHEMBL29625710 0.85 EPHX1 (0.49) KMT2AMEN1CYP1A2EPHX1ALDH1A1
SCHEMBL216321 0.85 EPHX1 (0.49) KMT2AMEN1CYP1A2EPHX1ALDH1A1
SCHEMBL15356647 0.84 KMT2A (0.43) KMT2AMEN1CYP1A2ERBB2FYN
SCHEMBL13048901 0.80 EPHX1 (0.45) KMT2AMEN1CYP1A2EPHX1ALDH1A1
SCHEMBL2014907 0.80 EPHX1 (0.43) KMT2AMEN1CYP1A2EPHX1ALDH1A1
SCHEMBL216103 0.79 MTNR1A (0.46) KMT2AMEN1EPHX1PPARGALDH1A1
Ammonia Solution, Strong SCHEMBL29224022 0.78 MTNR1A (0.45) KMT2AMEN1EPHX1PPARGALDH1A1
SCHEMBL29503667 0.78 MEN1 (0.43) KMT2AMEN1EPHX1PPARGALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1928979-A1 FUNCTIONALIZED PHOTOREACTIVE COMPOUNDS Rolic AG (CH) 2008-06-11 EP disclosed
WO-2007033506-A1 FUNCTIONALIZED PHOTOREACTIVE COMPOUNDS ROLIC AG (CH) 2007-03-29 WO disclosed