Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 17/20 | 0.73 |
| ▸ | ITGA4 | P13612 | 17/20 | 0.73 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5071945 | 0.86 | ITGB1 (0.83) | ITGB1ITGA4 | |
| SCHEMBL5069258 | 0.84 | ITGB1 (1.00) | ITGB1ITGA4 | |
| SCHEMBL5072077 | 0.81 | ITGB1 (0.79) | ITGB1ITGA4MAPTKDM4EMEN1 | |
| SCHEMBL5071960 | 0.78 | ITGB1 (0.83) | ITGB1ITGA4 | |
| SCHEMBL5069261 | 0.75 | ITGB1 (0.75) | ITGB1ITGA4 | |
| SCHEMBL5072034 | 0.75 | ITGB1 (0.75) | ITGB1ITGA4MAPTKDM4EMEN1 | |
| SCHEMBL5068926 | 0.74 | ITGB1 (1.00) | ITGB1ITGA4 | |
| SCHEMBL5066874 | 0.74 | ITGB1 (1.00) | ITGB1ITGA4 | |
| SCHEMBL6799221 | 0.74 | RAB9A (0.73) | ITGB1ITGA4MAPTMEN1RECQL | |
| SCHEMBL5071952 | 0.73 | ITGB1 (0.84) | ITGB1ITGA4MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7410984-B2 | Compounds | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2008-08-12 | — | — | US | claimed |