SCHEMBL5072094

SCHEMBL5072094

CCN1c2ccccc2N(C)c2ccccc21

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.44
LMNA P02545 3/20 0.44
MAOA P21397 1/20 0.44
CHRM2 P08172 1/20 0.44
HTR1A P08908 1/20 0.44
ADRA2A P08913 1/20 0.44
DRD2 P14416 1/20 0.44
DRD1 P21728 1/20 0.44
SLC6A2 P23975 1/20 0.44
HTR2A P28223 1/20 0.44
SLC6A4 P31645 1/20 0.44
HTR7 P34969 1/20 0.44
ADRA1A P35348 1/20 0.44
HRH1 P35367 1/20 0.44
OPRM1 P35372 1/20 0.44
DRD3 P35462 1/20 0.44
HTR6 P50406 1/20 0.44
POLB P06746 2/20 0.41
KMT2A Q03164 6/20 0.38
KDM4E B2RXH2 3/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL474136 0.89 POLB (0.46) MAPTLMNAPOLBKMT2AKDM4E
SCHEMBL29699888 0.89 POLB (0.46) MAPTLMNAPOLBKMT2AKDM4E
SCHEMBL2877910 0.89
SCHEMBL482716 0.81 MAOA (0.60) MAPTLMNAMAOACHRM2HTR1A
SCHEMBL29390564 0.81 MAOA (0.60) MAPTLMNAMAOACHRM2HTR1A
SCHEMBL13636983 0.81
SCHEMBL4571020 0.81 MAOA (0.60) MAPTLMNAMAOACHRM2HTR1A
SCHEMBL21311761 0.80 MAPT (0.67) MAPTLMNACHRM2HTR1AADRA2A
SCHEMBL23890049 0.79 ALDH1A1 (0.49) MAPTLMNACHRM2HTR1AADRA2A
SCHEMBL7450815 0.76 CDC25A (0.56) LMNAKMT2AKDM4EMEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7450293-B2 Electrochromic salts, solutions, and devices LOS ALAMOS NATIONAL SECURITY, LLC (US) 2008-11-11 US claimed
US-7436570-B2 Electrochromic salts, solutions, and devices LOS ALAMOS NATIONAL SECURITY, LLC (US) 2008-10-14 US claimed
EP-1457813-B1 An improved electrochromic medium capable of producing a pre-selected color GENTEX CORP (US) 2007-01-24 EP claimed
US-20050151467-A1 Electrochromic salts, solutions, and devices TRIAD NATIONAL SECURITY, LLC 2005-07-14 US claimed
US-20050116627-A1 Electrochromic salts, solutions, and devices TRIAD NATIONAL SECURITY, LLC 2005-06-02 US claimed
EP-1457813-A2 An improved electrochromic medium capable of producing a pre-selected color Gentex Corporation (US) 2004-09-15 EP claimed
EP-0972227-B1 AN IMPROVED ELECTROCHROMIC MEDIUM CAPABLE OF PRODUCING A PRE-SELECTED COLOR GENTEX CORP (US) 2004-07-14 EP claimed
WO-2004000800-A2 ELECTROCHROMIC SALTS, SOLUTIONS, AND DEVICES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2003-12-31 WO claimed
US-20030234379-A1 Electrochromic salts, solutions, and devices LOS ALAMOS NATIONAL SECURITY, LLC 2003-12-25 US claimed
US-6020987-A Electrochromic medium capable of producing a pre-selected color GENTEX CORPORATION (US) 2000-02-01 US claimed
US-5393606-A Electroconductivity CIBA-GEIGY CORPORATION (US) 1995-02-28 US claimed
EP-0588759-A1 Dithiopentacene derivatives, their preparation and their use in charge-transfer complexes CIBA-GEIGY AG (CH) 1994-03-23 EP claimed
EP-0573387-A2 Charge-transfer complex with N-aromatic compounds, their preparation and their use CIBA-GEIGY AG (CH) 1993-12-08 EP claimed
EP-3221420-B1 PHOTOCHROMIC-ELECTROCHROMIC COMPOSITIONS SWITCH MAT INC (CA) 2021-02-17 EP disclosed
US-10647913-B2 Photochromic-electrochromic compositions SWITCH MATERIALS INC. (CA) 2020-05-12 US disclosed
US-20170355901-A1 PHOTOCHROMIC-ELECTROCHROMIC COMPOSITIONS SOLUTIA CANADA INC. (CA) 2017-12-14 US disclosed
WO-1998044384-A1 AN IMPROVED ELECTROCHROMIC MEDIUM CAPABLE OF PRODUCING A PRE-SELECTED COLOR GENTEX CORPORATION (US) 1998-10-08 WO disclosed
US-5393606-A Electroconductivity CIBA-GEIGY CORPORATION (US) 1995-02-28 US disclosed
EP-0588759-A1 Dithiopentacene derivatives, their preparation and their use in charge-transfer complexes CIBA-GEIGY AG (CH) 1994-03-23 EP disclosed
EP-0573387-A2 Charge-transfer complex with N-aromatic compounds, their preparation and their use CIBA-GEIGY AG (CH) 1993-12-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050151467-A1 Electrochromic salts, solutions, and devices F8, ETV6, HCN4 MAPT 2765/4885LMNA 4162/4885MAOA 4465/4885
US-20050116627-A1 Electrochromic salts, solutions, and devices F8, ETV6, HCN4 MAPT 2765/4885LMNA 4162/4885MAOA 4465/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.