Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 3/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.31 |
| ▸ | VCP | P55072 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1777955 | 0.71 | CCNB2 (0.54) | — | |
| SCHEMBL7402425 | 0.62 | POLB (0.34) | — | |
| SCHEMBL8676051 | 0.60 | GAA (0.39) | — | |
| SCHEMBL12650917 | 0.60 | EGFR (0.30) | — | |
| SCHEMBL30966776 | 0.60 | RXRA (0.39) | — | |
| SCHEMBL14733919 | 0.58 | BCHE (0.42) | — | |
| SCHEMBL28796038 | 0.57 | BCHE (0.40) | — | |
| SCHEMBL9315 | 0.57 | — | — | |
| SCHEMBL9912056 | 0.56 | TAAR1 (0.37) | KCNH2 | |
| SCHEMBL23144903 | 0.56 | CXCR4 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1990343-A2 | Azaindoles | Aventis Pharma Limited (GB) | 2008-11-12 | — | — | EP | disclosed |