Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 2/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.36 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.36 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PRKDC | P78527 | 1/20 | 0.33 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14733974 | 0.77 | TLR8 (0.41) | BCHETLR8LIPGKDM4EMAPT | |
| SCHEMBL28796038 | 0.77 | BCHE (0.40) | BCHELIPGKDM4EGAAMAPT | |
| SCHEMBL14733975 | 0.75 | SLC2A1 (0.56) | KDM4E | |
| SCHEMBL14733857 | 0.75 | SLC2A1 (0.56) | KDM4E | |
| SCHEMBL14733918 | 0.73 | SLC2A1 (0.57) | KDM4E | |
| SCHEMBL8676051 | 0.73 | GAA (0.39) | BCHELIPGKDM4EGAAMAPT | |
| SCHEMBL2178352 | 0.71 | LIPG (0.47) | BCHELIPGMCL1KCNH3 | |
| SCHEMBL12861336 | 0.71 | KDM4E (0.42) | KDM4EGAAMAPT | |
| SCHEMBL9340104 | 0.71 | GAA (0.52) | SIGMAR1MCL1KDM4EGAAMAPT | |
| SCHEMBL2313397 | 0.69 | MTNR1A (0.41) | SIGMAR1MCL1KDM4EGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2331552-B1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2013-02-27 | — | — | EP | disclosed |