Styrene

Styrene

SCHEMBL5072103

C=C.C=CO.C=COC(C)=O.C=Cc1ccccc1

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.48
TSHR P16473 2/20 0.48
AKR1C3 P42330 1/20 0.39
GLA P06280 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
KMT2A Q03164 2/20 0.34
RECQL P46063 1/20 0.34
MEN1 O00255 1/20 0.34
CYP2C19 P33261 1/20 0.34
PTGS2 P35354 1/20 0.34
HTT P42858 1/20 0.33
AKT1 P31749 1/20 0.33
HDAC3 O15379 1/20 0.33
TNKS O95271 1/20 0.33
HDAC4 P56524 1/20 0.33
HDAC1 Q13547 1/20 0.33
HCAR2 Q8TDS4 1/20 0.33
HDAC7 Q8WUI4 1/20 0.33
HDAC2 Q92769 1/20 0.33
HDAC10 Q969S8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL21448340 0.96 ALDH1A1 (0.52) ALDH1A1TSHRAKR1C3GLATDP1
Styrene SCHEMBL10608565 0.96 ALDH1A1 (0.52) ALDH1A1TSHRAKR1C3GLATDP1
Styrene SCHEMBL9640408 0.95 ALDH1A1 (0.54) ALDH1A1TSHRAKR1C3GLATDP1
Styrene SCHEMBL381689 0.95 ALDH1A1 (0.54) ALDH1A1TSHRAKR1C3GLATDP1
Styrene SCHEMBL28187565 0.95 ALDH1A1 (0.54) ALDH1A1TSHRAKR1C3GLATDP1
Styrene SCHEMBL23462407 0.93 ALDH1A1 (0.48) ALDH1A1TSHRAKR1C3GLATDP1
Styrene SCHEMBL8098448 0.91 ALDH1A1 (0.50) ALDH1A1TSHRAKR1C3GLATDP1
Styrene SCHEMBL28467144 0.90 ALDH1A1 (0.48) ALDH1A1TSHRAKR1C3GLATDP1
Styrene SCHEMBL273537 0.90 ALDH1A1 (0.48) ALDH1A1TSHRAKR1C3GLATDP1
Styrene SCHEMBL3419207 0.90 ALDH1A1 (0.48) ALDH1A1TSHRAKR1C3GLATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101300016-A Antimicrobial polymers ISP INVESTMENTS INC (US) 2008-11-05 CN disclosed
EP-1940420-A2 ANTIMICROBIAL POLYMERS ISP INVESTMENTS INC. (US) 2008-07-09 EP disclosed
WO-2007021499-A2 ANTIMICROBIAL POLYMERS ISP INVESTMENTS INC. (US) 2007-02-22 WO disclosed