Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4349860 | 0.87 | REN (0.58) | RENCYP3A4 | |
| SCHEMBL5072287 | 0.87 | REN (0.62) | RENCYP3A4 | |
| SCHEMBL661617 | 0.82 | REN (0.57) | RENCYP3A4 | |
| SCHEMBL661619 | 0.82 | REN (0.57) | RENCYP3A4 | |
| SCHEMBL4351920 | 0.81 | REN (0.58) | RENCYP3A4 | |
| SCHEMBL4354028 | 0.81 | REN (0.56) | RENCYP3A4 | |
| SCHEMBL5069667 | 0.81 | REN (0.56) | RENCYP3A4 | |
| SCHEMBL5072291 | 0.80 | REN (0.65) | RENCYP3A4 | |
| SCHEMBL4349864 | 0.80 | REN (0.75) | RENCYP3A4 | |
| SCHEMBL4353647 | 0.80 | REN (0.56) | RENCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1910272-A1 | RENIN INHIBITORS | Merck Frosst Canada Ltd. (CA) | 2008-04-16 | — | — | EP | disclosed |
| WO-2007009250-A1 | RENIN INHIBITORS | MERCK FROSST CANADA LTD. (CA) | 2007-01-25 | — | — | WO | disclosed |