Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.63 |
| ▸ | THRB | P10828 | 1/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | EGFR | P00533 | 4/20 | 0.55 |
| ▸ | ERBB2 | P04626 | 4/20 | 0.55 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | ESR1 | P03372 | 1/20 | 0.49 |
| ▸ | CA3 | P07451 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | TYR | P14679 | 1/20 | 0.49 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.49 |
| ▸ | CA4 | P22748 | 1/20 | 0.49 |
| ▸ | CA6 | P23280 | 1/20 | 0.49 |
| ▸ | DPP4 | P27487 | 1/20 | 0.49 |
| ▸ | CA5A | P35218 | 1/20 | 0.49 |
| ▸ | CA7 | P43166 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5070917 | 1.00 | KMT2A (0.63) | KMT2ATHRBATMEGFRERBB2 | |
| SCHEMBL3169519 | 0.98 | KMT2A (0.65) | KMT2ATHRBATMEGFRERBB2 | |
| SCHEMBL3169514 | 0.98 | KMT2A (0.65) | KMT2ATHRBATMEGFRERBB2 | |
| SCHEMBL22510783 | 0.94 | KMT2A (0.59) | KMT2ATHRBATMEGFRERBB2 | |
| SCHEMBL28181478 | 0.93 | AKR1C3 (0.58) | KMT2ATHRBATMEGFRERBB2 | |
| SCHEMBL28633075 | 0.93 | AKR1C3 (0.58) | KMT2ATHRBATMEGFRERBB2 | |
| SCHEMBL13481049 | 0.92 | THRB (0.61) | KMT2ATHRBATMEGFRERBB2 | |
| SCHEMBL10389632 | 0.91 | AKR1C3 (0.59) | KMT2ATHRBATMEGFRERBB2 | |
| SCHEMBL22510785 | 0.91 | KMT2A (0.58) | KMT2ATHRBATMEGFRERBB2 | |
| SCHEMBL10389633 | 0.91 | AKR1C3 (0.59) | KMT2ATHRBATMEGFRERBB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1948203-A2 | AROMATIC DI-ACID-CONTAINING POLY (ESTER AMIDE) POLYMERS AND METHODS OF USE | Medivas, LLC (US) | 2008-07-30 | — | — | EP | claimed |
| US-20070106035-A1 | Aromatic di-acid-containing poly (ester amide) polymers and methods of use | MEDIVAS, LLC (US) | 2007-05-10 | — | — | US | claimed |
| WO-2007050583-A2 | AROMATIC DI-ACID-CONTAINING POLY (ESTER AMIDE) POLYMERS AND METHODS OF USE | MEDIVAS, LLC (US) | 2007-05-03 | — | — | WO | claimed |
| EP-1948203-A2 | AROMATIC DI-ACID-CONTAINING POLY (ESTER AMIDE) POLYMERS AND METHODS OF USE | Medivas, LLC (US) | 2008-07-30 | — | — | EP | disclosed |
| US-20070106035-A1 | Aromatic di-acid-containing poly (ester amide) polymers and methods of use | MEDIVAS, LLC (US) | 2007-05-10 | — | — | US | disclosed |
| WO-2007050583-A2 | AROMATIC DI-ACID-CONTAINING POLY (ESTER AMIDE) POLYMERS AND METHODS OF USE | MEDIVAS, LLC (US) | 2007-05-03 | — | — | WO | disclosed |