Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.65 |
| ▸ | THRB | P10828 | 1/20 | 0.57 |
| ▸ | ATM | Q13315 | 1/20 | 0.57 |
| ▸ | EGFR | P00533 | 4/20 | 0.56 |
| ▸ | ERBB2 | P04626 | 4/20 | 0.56 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.50 |
| ▸ | CA3 | P07451 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | TYR | P14679 | 1/20 | 0.50 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.50 |
| ▸ | CA4 | P22748 | 1/20 | 0.50 |
| ▸ | CA6 | P23280 | 1/20 | 0.50 |
| ▸ | DPP4 | P27487 | 1/20 | 0.50 |
| ▸ | CA5A | P35218 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3169519 | 1.00 | KMT2A (0.65) | KMT2ATHRBATMEGFRERBB2 | |
| SCHEMBL5070917 | 0.98 | KMT2A (0.63) | KMT2ATHRBATMEGFRERBB2 | |
| SCHEMBL5072562 | 0.98 | KMT2A (0.63) | KMT2ATHRBATMEGFRERBB2 | |
| SCHEMBL22510783 | 0.95 | KMT2A (0.59) | KMT2ATHRBATMEGFRERBB2 | |
| SCHEMBL13481049 | 0.93 | THRB (0.61) | KMT2ATHRBATMEGFRERBB2 | |
| SCHEMBL10389632 | 0.93 | AKR1C3 (0.59) | KMT2ATHRBATMEGFRERBB2 | |
| SCHEMBL22510785 | 0.93 | KMT2A (0.58) | KMT2ATHRBATMEGFRERBB2 | |
| SCHEMBL10389633 | 0.93 | AKR1C3 (0.59) | KMT2ATHRBATMEGFRERBB2 | |
| SCHEMBL22510786 | 0.92 | EGFR (0.56) | KMT2ATHRBATMEGFRERBB2 | |
| SCHEMBL28633075 | 0.91 | AKR1C3 (0.58) | KMT2ATHRBATMEGFRERBB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7649022-B2 | Bioabsorbable elastomeric polymer networks, cross-linkers and methods of use | MEDIVAS, LLC (US) | 2010-01-19 | — | — | US | claimed |
| US-20090253809-A1 | BIOABSORBABLE ELASTOMERIC POLYMER NETWORKS, CROSS-LINKERS AND METHODS OF USE | MEDIVAS, LLC (US) | 2009-10-08 | — | — | US | claimed |
| EP-1948203-A2 | AROMATIC DI-ACID-CONTAINING POLY (ESTER AMIDE) POLYMERS AND METHODS OF USE | Medivas, LLC (US) | 2008-07-30 | — | — | EP | claimed |
| US-20070106035-A1 | Aromatic di-acid-containing poly (ester amide) polymers and methods of use | MEDIVAS, LLC (US) | 2007-05-10 | — | — | US | claimed |
| WO-2007050583-A2 | AROMATIC DI-ACID-CONTAINING POLY (ESTER AMIDE) POLYMERS AND METHODS OF USE | MEDIVAS, LLC (US) | 2007-05-03 | — | — | WO | claimed |
| US-8652504-B2 | Solid polymer delivery compositions and methods for use thereof | MEDIVAS, LLC (US) | 2014-02-18 | — | — | US | disclosed |
| EP-1986685-A4 | VACCINE DELIVERY COMPOSITIONS AND METHODS OF USE | MEDIVAS LLC (US) | 2009-02-25 | — | — | EP | disclosed |
| EP-1986685-A2 | VACCINE DELIVERY COMPOSITIONS AND METHODS OF USE | Medivas, LLC (US) | 2008-11-05 | — | — | EP | disclosed |
| EP-1962894-A2 | METHOD FOR ASSEMBLING A POLYMER-BIOLOGIC DELIVERY COMPOSITION | Medivas, LLC (US) | 2008-09-03 | — | — | EP | disclosed |
| EP-1957113-A2 | POLYMER PARTICLES FOR DELIVERY OF MACROMOLECULES AND METHODS OF USE | Medivas, LLC (US) | 2008-08-20 | — | — | EP | disclosed |
| EP-1948203-A2 | AROMATIC DI-ACID-CONTAINING POLY (ESTER AMIDE) POLYMERS AND METHODS OF USE | Medivas, LLC (US) | 2008-07-30 | — | — | EP | disclosed |
| WO-2008048298-A2 | POLYMER PARTICLES FOR DELIVERY OF MACROMOLECULES AND METHODS OF USE | MEDIVAS, LLC (US) | 2008-04-24 | — | — | WO | disclosed |
| US-20070160622-A1 | Method for assembling a polymer-biologic delivery composition | MEDIVAS, LLC (US) | 2007-07-12 | — | — | US | disclosed |
| US-20070134332-A1 | Polymer particles for delivery of macromolecules and methods of use | MEDIVAS, LLC (US) | 2007-06-14 | — | — | US | disclosed |
| WO-2007067744-A2 | METHOD FOR ASSEMBLING A POLYMER-BIOLOGIC DELIVERY COMPOSITION | MEDIVAS, LLC (US) | 2007-06-14 | — | — | WO | disclosed |
| US-20070106035-A1 | Aromatic di-acid-containing poly (ester amide) polymers and methods of use | MEDIVAS, LLC (US) | 2007-05-10 | — | — | US | disclosed |
| US-20070106035-A1 | Aromatic di-acid-containing poly (ester amide) polymers and methods of use | MEDIVAS, LLC (US) | 2007-05-10 | — | — | US | disclosed |
| WO-2007050583-A2 | AROMATIC DI-ACID-CONTAINING POLY (ESTER AMIDE) POLYMERS AND METHODS OF USE | MEDIVAS, LLC (US) | 2007-05-03 | — | — | WO | disclosed |
| US-20060188469-A1 | Vaccine delivery compositions and methods of use | MEDIVAS, LLC (US) | 2006-08-24 | — | — | US | disclosed |
| WO-2006083874-A2 | VACCINE DELIVERY COMPOSITIONS AND METHODS OF USE | MEDIVAS, LLC. (US) | 2006-08-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090253809-A1 | BIOABSORBABLE ELASTOMERIC POLYMER NETWORKS, CROSS-LINKERS AND METHODS OF USE | FAU, PEF1, APEH | KMT2A 2394/4885THRB 3264/4885ATM 3418/4885 |
| US-20070134332-A1 | Polymer particles for delivery of macromolecules and methods of use | IAPP, PLAU, PLAUR | KMT2A 4188/4885THRB 3119/4885ATM 2008/4885 |
| US-20070160622-A1 | Method for assembling a polymer-biologic delivery composition | CD40, FCGR3B, TNFRSF9 | KMT2A 3600/4885THRB 3004/4885ATM 4858/4885 |
| US-20060188469-A1 | Vaccine delivery compositions and methods of use | PUF60, UACA, USP36 | KMT2A 2753/4885THRB 4492/4885ATM 3063/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.