SCHEMBL5072589

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nearest known ligand 0.36

Predicted protein targets (top 6)

	gene	UniProt	supporting neighbours	confidence
▸	OPRM1	P35372	6/20	0.36

▸	OPRD1	P41143	6/20	0.36

▸	OPRK1	P41145	2/20	0.36

▸	TERT	O14746	1/20	0.32

▸	PRMT1	Q99873	1/20	0.32

▸	KEAP1	Q14145	1/20	0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL5069096	0.88	OPRM1 (0.31)	OPRM1OPRD1KEAP1
SCHEMBL4089483	0.87	OPRM1 (0.42)	OPRM1OPRD1OPRK1TERTPRMT1
SCHEMBL4089476	0.87	OPRM1 (0.42)	OPRM1OPRD1OPRK1TERTPRMT1
SCHEMBL4089047	0.86	OPRM1 (0.37)	OPRM1OPRD1OPRK1
SCHEMBL4100066	0.83	MME (0.34)	OPRM1OPRD1OPRK1
SCHEMBL4094324	0.82	TERT (0.42)	OPRM1OPRD1OPRK1TERTPRMT1
SCHEMBL4094331	0.82	TERT (0.42)	OPRM1OPRD1OPRK1TERTPRMT1
SCHEMBL4082724	0.81	OPRM1 (0.33)	OPRM1OPRD1OPRK1
SCHEMBL4092941	0.81	MME (0.39)	—
SCHEMBL4099169	0.80	TERT (0.38)	OPRM1OPRD1OPRK1TERT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-2007794-A1	LYSOBACTIN AMIDES	AiCuris GmbH & Co. KG (DE)	2008-12-31	—	—	EP	disclosed
WO-2007118691-A1	LYSOBACTIN AMIDES	AICURIS GMBH & CO. KG (DE)	2007-10-25	—	—	WO	disclosed