Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | GSTK1 | Q9Y2Q3 | 1/20 | 0.43 |
| ▸ | NOD1 | Q9Y239 | 12/20 | 0.39 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.35 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | FNTA | P49354 | 1/20 | 0.31 |
| ▸ | FNTB | P49356 | 1/20 | 0.31 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL246687 | 0.88 | PTGS1 (0.46) | PTGS1GSTK1NOD1GLO1FOLH1 | |
| SCHEMBL2532429 | 0.82 | PTGS1 (0.53) | PTGS1GSTK1NOD1GLO1FOLH1 | |
| SCHEMBL235440 | 0.82 | PTGS1 (0.56) | PTGS1GSTK1NOD1GLO1FOLH1 | |
| SCHEMBL4213412 | 0.81 | NOD1 (0.41) | PTGS1GSTK1NOD1GLO1 | |
| SCHEMBL15668617 | 0.80 | PTGS1 (0.54) | PTGS1GSTK1NOD1GLO1FOLH1 | |
| SCHEMBL2530952 | 0.79 | PTGS1 (0.65) | PTGS1GSTK1NOD1GLO1FOLH1 | |
| SCHEMBL2534816 | 0.79 | PTGS1 (0.65) | PTGS1GSTK1NOD1GLO1FOLH1 | |
| Bromide SCHEMBL4250677 | 0.78 | PTGS1 (0.64) | PTGS1GSTK1NOD1GLO1FOLH1 | |
| SCHEMBL6657807 | 0.75 | PTGS1 (0.46) | PTGS1GSTK1NOD1GLO1FOLH1 | |
| SCHEMBL6664720 | 0.74 | PTGS1 (0.45) | PTGS1GSTK1NOD1GLO1FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1965650-A2 | COMPOSITIONS AND METHODS FOR ATTENUATING MITOCHONDRIA-MEDIATED CELL INJURY | University of Rochester (US) | 2008-09-10 | — | — | EP | disclosed |
| WO-2007076322-A2 | COMPOSITIONS AND METHODS FOR ATTENUATING MITOCHONDRIA-MEDIATED CELL INJURY | UNIVERSITY OF ROCHESTER (US) | 2007-07-05 | — | — | WO | disclosed |