Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.63 |
| ▸ | IAPP | P10997 | 4/20 | 0.60 |
| ▸ | FFAR1 | O14842 | 8/20 | 0.59 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.50 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.50 |
| ▸ | BID | P55957 | 1/20 | 0.49 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL244943 | 0.91 | IAPP (0.70) | KEAP1IAPPFFAR1AKR1B1PTGER1 | |
| SCHEMBL30485631 | 0.91 | IAPP (0.70) | KEAP1IAPPFFAR1AKR1B1PTGER1 | |
| Ammonia Solution, Strong SCHEMBL31621217 | 0.90 | IAPP (0.68) | KEAP1IAPPFFAR1AKR1B1PTGER1 | |
| SCHEMBL1426622 | 0.82 | IAPP (0.52) | IAPPBIDBCL2L1MCL1BAK1 | |
| SCHEMBL21317650 | 0.81 | FFAR1 (0.47) | IAPPFFAR1FFAR4AKR1B1 | |
| SCHEMBL16795917 | 0.81 | IAPP (0.61) | IAPPHDAC3MAPK1ADRA1AHDAC4 | |
| SCHEMBL490805 | 0.80 | TDP1 (0.61) | IAPPMAPK1SMN1; SMN2BIDBCL2L1 | |
| SCHEMBL35529 | 0.80 | AKR1B1 (0.65) | KEAP1IAPPFFAR1HDAC3MAPK1 | |
| SCHEMBL29373796 | 0.80 | AKR1B1 (0.65) | KEAP1IAPPFFAR1HDAC3MAPK1 | |
| SCHEMBL7128255 | 0.80 | AKR1B1 (0.65) | KEAP1IAPPFFAR1HDAC3MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1476181-A4 | POLYALKYLENE POLYMER COMPOUNDS AND USES THEREOF | BIOGEN IDEC INC (US) | 2008-11-19 | — | — | EP | disclosed |
| EP-1476181-A2 | POLYALKYLENE POLYMER COMPOUNDS AND USES THEREOF | Biogen Idec MA Inc. (US) | 2004-11-17 | — | — | EP | disclosed |
| WO-2003061577-A2 | POLYALKYLENE GLYCOL WITH MOIETY FOR CONJUGATING BIOLOGICALLY ACTIVE COMPOUND | BIOGEN IDEC MA INC. (US) | 2003-07-31 | — | — | WO | disclosed |