Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.65 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.56 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.54 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.51 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.51 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.51 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.51 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.50 |
| ▸ | IAPP | P10997 | 1/20 | 0.48 |
| ▸ | MPO | P05164 | 2/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL35529 | 1.00 | AKR1B1 (0.65) | AKR1B1KEAP1TAAR1FFAR1POLB | |
| SCHEMBL29373796 | 1.00 | AKR1B1 (0.65) | AKR1B1KEAP1TAAR1FFAR1POLB | |
| Methane SCHEMBL1275762 | 0.98 | AKR1B1 (0.63) | AKR1B1KEAP1TAAR1FFAR1POLB | |
| Butane SCHEMBL28254816 | 0.92 | AKR1B1 (0.57) | AKR1B1KEAP1TAAR1FFAR1POLB | |
| SCHEMBL1827150 | 0.88 | AKR1B1 (0.61) | AKR1B1KEAP1TAAR1FFAR1HSPA5 | |
| SCHEMBL59198 | 0.86 | KEAP1 (0.65) | AKR1B1KEAP1FFAR1PTGER1PTGER4 | |
| SCHEMBL3623274 | 0.86 | AKR1B1 (0.59) | AKR1B1TAAR1IAPPMPOHDAC3 | |
| SCHEMBL11751573 | 0.84 | IAPP (0.59) | AKR1B1TAAR1HSPA5IAPPMPO | |
| SCHEMBL16230472 | 0.84 | MAPT (0.61) | AKR1B1IAPPHDAC3MAPK1ADRA1A | |
| SCHEMBL17078364 | 0.84 | MAPT (0.61) | AKR1B1IAPPHDAC3MAPK1ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6660524-B1 | First nucleic acid sequence linked to and regulates expression of a second nucleic acid sequence that encodes a regulator polypeptide; and a third nucleic acid sequence linked to and regulates expression of a target nucleic acid | ADVANCED TECHNOLOGIES (CAMBRIDGE) LIMITED (GB) | 2003-12-09 | — | — | US | claimed |