SCHEMBL5074121

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5072021	0.81	KDM4E (0.48)	PARP1DHODHPARP2CDC7BTK
	SCHEMBL5076325	0.80	ADORA3 (0.44)	PARP1DHODHPARP2CDC7KDM4E
	SCHEMBL5752743	0.78	PARP1 (0.40)	PARP1DHODHKDM4EALDH1A1CHEK2
	SCHEMBL6029199	0.78	CDC7 (0.53)	PARP1DHODHPARP2CDC7BTK
	SCHEMBL5076412	0.78	NPC1 (0.45)	PARP1DHODHCDC7KDM4EALDH1A1
	SCHEMBL5071975	0.78	CDC7 (0.58)	PARP1PARP2CDC7BTKCHEK2
	SCHEMBL5074093	0.77	KDM4E (0.53)	PARP1DHODHKDM4EALDH1A1NPC1
	SCHEMBL4342616	0.77	CDC7 (0.61)	PARP1DHODHPARP2CDC7BTK
	SCHEMBL5071999	0.77	CDC7 (0.48)	PARP1DHODHPARP2CDC7KDM4E
	SCHEMBL5074231	0.77	KDM4E (0.45)	PARP1CDC7BTKKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.