Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 2/20 | 0.33 |
| ▸ | LOX | P28300 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL789133 | 1.00 | ALDH1A1 (0.41) | ALDH1A1LMNATP53NLRP3FAAH | |
| SCHEMBL322671 | 1.00 | ALDH1A1 (0.41) | ALDH1A1LMNATP53NLRP3FAAH | |
| SCHEMBL788984 | 1.00 | ALDH1A1 (0.41) | ALDH1A1LMNATP53NLRP3FAAH | |
| SCHEMBL7860230 | 1.00 | ALDH1A1 (0.41) | ALDH1A1LMNATP53NLRP3FAAH | |
| SCHEMBL8489437 | 1.00 | ALDH1A1 (0.41) | ALDH1A1LMNATP53NLRP3FAAH | |
| SCHEMBL794694 | 1.00 | ALDH1A1 (0.41) | ALDH1A1LMNATP53NLRP3FAAH | |
| SCHEMBL788478 | 0.97 | — | — | |
| SCHEMBL148081 | 0.88 | — | — | |
| SCHEMBL9185106 | 0.85 | ALDH1A1 (0.50) | ALDH1A1LMNATP53NLRP3FAAH | |
| SCHEMBL5461072 | 0.85 | ALDH1A1 (0.50) | ALDH1A1LMNATP53NLRP3FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1697465-B1 | POLYMER NANOCOMPOSITES AND METHODS FOR THEIR PREPARATION | GEN ELECTRIC (US) | 2008-02-13 | — | — | EP | disclosed |
| EP-1697465-A2 | POLYMER NANOCOMPOSITES AND METHODS FOR THEIR PREPARATION | GENERAL ELECTRIC COMPANY (US) | 2006-09-06 | — | — | EP | disclosed |
| WO-2005061623-A2 | POLYMER NANOCOMPOSITES AND METHODS FOR THEIR PREPARATION | GENERAL ELECTRIC COMPANY (US) | 2005-07-07 | — | — | WO | disclosed |
| US-20050137310-A1 | Polymer nanocomposites and methods for their preparation | CITIBANK, N.A., AS COLLATERAL AGENT | 2005-06-23 | — | — | US | disclosed |