SCHEMBL788478

SCHEMBL788478

[CH2]CCCCS(C)(=O)=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL794694 0.97 ALDH1A1 (0.41)
SCHEMBL322671 0.97 ALDH1A1 (0.41)
SCHEMBL789133 0.97 ALDH1A1 (0.41)
SCHEMBL7860230 0.97 ALDH1A1 (0.41)
SCHEMBL8489437 0.97 ALDH1A1 (0.41)
SCHEMBL5074185 0.97 ALDH1A1 (0.41)
SCHEMBL788984 0.97 ALDH1A1 (0.41)
SCHEMBL148081 0.91
SCHEMBL777321 0.84 ALDH1A1 (0.52)
SCHEMBL9185106 0.81 ALDH1A1 (0.50)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 144 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1517886-B1 NOVEL PHTHALAMIDE DERIVATIVES BAYER CROPSCIENCE AG (DE) 2010-11-10 EP claimed
US-7132455-B2 Phthalamide derivatives BAYER CROPSCIENCE AG (DE) 2006-11-07 US claimed
US-20060035967-A1 Novel phthalamide derivatives BAYER INTELLECTUAL PROPERTY GMBH (DE) 2006-02-16 US claimed
WO-2006016903-A2 1, 2,4-TRIOXANES AND 1, 2, 4-TRIOXEPANES ROMARK LABORATORIES, L.C. (US) 2006-02-16 WO claimed
EP-1472254-A4 PURINE AND ISOSTERIC ANTIBACTERIAL COMPOUNDS GLSYNTHESIS INC (US) 2006-02-15 EP claimed
US-20050256184-A1 1,2,4-Trioxanes and 1,2,4-trioxepanes O'NEILL PAUL M 2005-11-17 US claimed
US-6926763-B2 Purine and isosteric antibacterial compounds GLSYNTHESIS, INC. (US) 2005-08-09 US claimed
EP-1517886-A1 NOVEL PHTHALAMIDE DERIVATIVES Bayer CropScience AG (DE) 2005-03-30 EP claimed
EP-1472254-A2 PURINE AND ISOSTERIC ANTIBACTERIAL COMPOUNDS Glsynthesis Inc. (US) 2004-11-03 EP claimed
US-20040014773-A1 Purine and isosteric antibacterial compounds ACURX PHARMACEUTICALS, LLC 2004-01-22 US claimed
US-5559110-A HIV ANTIVIRAL, GOOD SYSTEMIC ABSORPTION ADMINISTERED BY MOUTH THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) 1996-09-24 US claimed
US-5543517-A VIRICIDES THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) 1996-08-06 US claimed
US-5532357-A Method for preparing N-monosubstituted and N,N'-disubstituted unsymmetrical cyclic ureas THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) 1996-07-02 US claimed
EP-0691961-A1 SUBSTITUTED CAPROLACTAMS AND DERIVATIVES THEREOF USEFUL FOR TREATMENT OF HIV DISEASE THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) 1996-01-17 EP claimed
WO-1996000708-A1 METHOD FOR PREPARING ALKYLATING AGENTS AND THEIR USE FOR ALKYLATING CYCLIC UREAS THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) 1996-01-11 WO claimed
EP-0686151-A1 SUBSTITUTED CYCLIC CARBONYLS AND DERIVATIVES THEREOF USEFUL AS RETROVIRAL PROTEASE INHIBITORS THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) 1995-12-13 EP claimed
WO-1994022840-A1 SUBSTITUTED CAPROLACTAMS AND DERIVATIVES THEREOF USEFUL FOR TREATMENT OF HIV DISEASE THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) 1994-10-13 WO claimed
WO-1994019329-A1 SUBSTITUTED CYCLIC CARBONYLS AND DERIVATIVES THEREOF USEFUL AS RETROVIRAL PROTEASE INHIBITORS THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) 1994-09-01 WO claimed
EP-0518939-A1 ANTIARRHYTHMIC AGENTS BTG INTERNATIONAL LIMITED (GB) 1992-12-23 EP claimed
WO-1991013865-A1 ANTIARRHYTHMIC AGENTS ISIS INNOVATION LIMITED (GB) 1991-09-19 WO claimed