Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23526429 | 0.79 | SMN1; SMN2 (0.32) | ADRB2ADRB1ADRB3CA1CA2 | |
| SCHEMBL23526565 | 0.78 | ADRB2 (0.31) | ADRB2ADRB1ADRB3 | |
| SCHEMBL14191180 | 0.76 | ADRB2 (0.33) | ADRB2ADRB1ADRB3CYP3A4TSHR | |
| SCHEMBL150402 | 0.76 | ADRB2 (0.41) | ADRB2ADRB1ADRB3CYP3A4TSHR | |
| SCHEMBL702262 | 0.76 | ADRB2 (0.41) | ADRB2ADRB1ADRB3CYP3A4TSHR | |
| SCHEMBL976747 | 0.76 | ADRB2 (0.41) | ADRB2ADRB1ADRB3CYP3A4TSHR | |
| SCHEMBL209438 | 0.75 | ADRB2 (0.32) | ADRB2ADRB1ADRB3 | |
| SCHEMBL430612 | 0.74 | ADRB2 (0.39) | ADRB2ADRB1ADRB3CYP3A4TSHR | |
| SCHEMBL15333887 | 0.74 | ADRB2 (0.39) | ADRB2ADRB1ADRB3CYP3A4TSHR | |
| SCHEMBL20394641 | 0.74 | ADRB2 (0.39) | ADRB2ADRB1ADRB3CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0845016-B1 | STABLE SILANE COMPOSITIONS ON SILICA CARRIER | GEN ELECTRIC (US) | 2004-07-07 | — | — | EP | claimed |
| US-7432321-B2 | Silica-rubber mixtures having improved hardness | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2008-10-07 | — | — | US | disclosed |
| US-20050277717-A1 | Silica-rubber mixtures having improved hardness | MOMENTIVE PERFORMANCE MATERIALS INC. | 2005-12-15 | — | — | US | disclosed |
| EP-1551913-A2 | SILICA-RUBBER MIXTURES HAVING IMPROVED HARDNESS | GENERAL ELECTRIC COMPANY (US) | 2005-07-13 | — | — | EP | disclosed |
| EP-0845016-B1 | STABLE SILANE COMPOSITIONS ON SILICA CARRIER | GEN ELECTRIC (US) | 2004-07-07 | — | — | EP | disclosed |
| WO-2004005395-A2 | SILICA-RUBBER MIXTURES HAVING IMPROVED HARDNESS | GENERAL ELECTRIC COMPANY (US) | 2004-01-15 | — | — | WO | disclosed |
| US-6005027-A | ELASTOMER AND BLEND WITH SILANE AND SILICA AND INFRARED ABSORBANCE | WITCO CORPORATION (US) | 1999-12-21 | — | — | US | disclosed |
| EP-0845016-A4 | STABLE SILANE COMPOSITIONS ON SILICA CARRIER | OSI SPECIALTIES INC (US) | 1999-04-14 | — | — | EP | disclosed |
| EP-0845016-A1 | STABLE SILANE COMPOSITIONS ON SILICA CARRIER | OSi Specialties, Inc. (US) | 1998-06-03 | — | — | EP | disclosed |
| WO-1997007165-A1 | STABLE SILANE COMPOSITIONS ON SILICA CARRIER | OSI SPECIALTIES, INC. (US) | 1997-02-27 | — | — | WO | disclosed |