SCHEMBL5074455

SCHEMBL5074455

Nc1cc(Cl)c(N)c(Cl)c1Cl

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.53
CYP3A4 P08684 7/20 0.48
ALDH1A1 P00352 3/20 0.48
CD44 P16070 1/20 0.42
CA1 P00915 5/20 0.37
CA2 P00918 5/20 0.37
CA9 Q16790 4/20 0.37
TSHR P16473 4/20 0.36
TP53 P04637 1/20 0.36
MAPK1 P28482 1/20 0.35
CA4 P22748 2/20 0.34
CA12 O43570 2/20 0.34
CA7 P43166 2/20 0.34
CA14 Q9ULX7 2/20 0.34
CA3 P07451 1/20 0.34
CA6 P23280 1/20 0.34
CA5A P35218 1/20 0.34
CA5B Q9Y2D0 1/20 0.34
POLB P06746 1/20 0.33
APEX1 P27695 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7289940 0.79 CYP3A4 (0.59) GAACYP3A4ALDH1A1CA1CA2
SCHEMBL3911038 0.79 CYP3A4 (0.59) GAACYP3A4ALDH1A1CD44CA1
SCHEMBL2593530 0.78 CYP3A4 (0.56) GAACYP3A4ALDH1A1CD44CA1
Hydrochloric Acid SCHEMBL11496367 0.77 CYP3A4 (0.56) GAACYP3A4ALDH1A1CD44CA1
SCHEMBL7210094 0.77 GAA (0.53) GAACYP3A4ALDH1A1CD44CA1
SCHEMBL1503430 0.77 ALDH1A1 (0.48) GAACYP3A4ALDH1A1CA1CA2
SCHEMBL10976016 0.76 CD44 (0.48) GAACYP3A4ALDH1A1CD44CA1
SCHEMBL10620711 0.72 ALDH1A1 (0.45) GAACYP3A4ALDH1A1CD44CA1
SCHEMBL28243782 0.71 GAA (0.46) GAACYP3A4ALDH1A1CD44CA1
SCHEMBL8321419 0.71 GAA (0.53) GAACYP3A4ALDH1A1CD44CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112301443-B Three-stage heat setting method of heterocyclic aramid fiber 中蓝晨光化工有限公司 2022-04-12 CN disclosed
CN-112301443-A Three-stage heat setting method of heterocyclic aramid fiber 中蓝晨光化工有限公司 2021-02-02 CN disclosed
US-20080124534-A1 Polyamide, Film, and Image Display Device FUJIFILM CORPORATION (JP) 2008-05-29 US disclosed
WO-2006030873-A1 POLYAMIDE, FILM, AND IMAGE DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2006-03-23 WO disclosed
US-4081439-A Aromatic disazo pigments CIBA-GEIGY CORPORATION (US) 1978-03-28 US disclosed
US-4070353-A FOR PLASTICS AND PRINTING INKS, YELLOW TO ORANGE SHADES CIBA-GEIGY CORPORATION (US) 1978-01-24 US disclosed
US-4065449-A Tetrachloro substituted disazo pigments CIBA-GEIGY CORPORATION (US) 1977-12-27 US disclosed
US-4062838-A LACQUERS, PRINTING INKS, YELLOW TO ORANGE CIBA-GEIGY CORPORATION (US) 1977-12-13 US disclosed
US-3988312-A TETRAKISAZO DYES CIBA-GEIGY CORPORATION (US) 1976-10-26 US disclosed
US-3978038-A POLYAMIDES, POLYESTERS, POLYURETHANES CIBA-GEIGY CORPORATION (US) 1976-08-31 US disclosed
US-3956266-A DISAZO DYES CIBA-GEIGY CORPORATION (US) 1976-05-11 US disclosed