Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRIM24 | O15164 | 1/20 | 0.52 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 8/20 | 0.50 |
| ▸ | CA12 | O43570 | 7/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | CA9 | Q16790 | 5/20 | 0.47 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.45 |
| ▸ | CDK4 | P11802 | 1/20 | 0.45 |
| ▸ | CCND1 | P24385 | 1/20 | 0.45 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.45 |
| ▸ | JUN | P05412 | 1/20 | 0.45 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.45 |
| ▸ | CA4 | P22748 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1838566 | 0.80 | TRIM24 (0.52) | TRIM24TRIM33CA2CA12KDM4E | |
| SCHEMBL1416793 | 0.78 | TRIM24 (0.62) | TRIM24TRIM33CA2CA12KDM4E | |
| SCHEMBL4630799 | 0.76 | TRPA1 (0.54) | TRIM24TRIM33CA2CA12KDM4E | |
| SCHEMBL13158791 | 0.76 | TRPA1 (0.54) | TRIM24TRIM33CA2CA12KDM4E | |
| SCHEMBL229461 | 0.76 | TRPA1 (0.54) | TRIM24TRIM33CA2CA12KDM4E | |
| SCHEMBL30528037 | 0.76 | TRPA1 (0.54) | TRIM24TRIM33CA2CA12KDM4E | |
| SCHEMBL15941726 | 0.75 | TRPA1 (0.47) | TRIM24TRIM33CA2CA12KDM4E | |
| SCHEMBL10923644 | 0.75 | TRPA1 (0.57) | TRIM24TRIM33CA2CA12KDM4E | |
| SCHEMBL3591597 | 0.75 | TRIM24 (0.46) | TRIM24TRIM33CA2CA12KDM4E | |
| SCHEMBL1759710 | 0.73 | NFE2L2 (0.54) | TRPA1NFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100432129-C | Thermal stabilizer compositions for halogen-containing vinyl polymers | ROHM & HAAS (US) | 2008-11-12 | — | — | CN | disclosed |
| EP-1881835-A1 | TRIAZINE COMPOUNDS AND COMPOSITIONS THEREOF FOR THE TREATMENT OF CANCERS | ProMetic BioSciences Inc. (CA) | 2008-01-30 | — | — | EP | disclosed |
| WO-2006122431-A1 | TRIAZINE COMPOUNDS AND COMPOSITIONS THEREOF FOR THE TREATMENT OF CANCERS | PROMETIC BIOSCIENCES INC. (CA) | 2006-11-23 | — | — | WO | disclosed |
| CN-1727383-A | Thermal stabilizer compositions for halogen-containing vinyl polymers | ROHM & HAAS (US) | 2006-02-01 | — | — | CN | disclosed |
| CN-1350027-A | Polymer composition containing halogen stabilized by crypto-thio-alcohol and mixture of zinc carboxylate and zinc chloride | ROHM & HAAS (US) | 2002-05-22 | — | — | CN | disclosed |