Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.40 |
| ▸ | HTR2A | P28223 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | THPO | P40225 | 1/20 | 0.40 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.40 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15673888 | 0.91 | TNFRSF1A (0.42) | NFE2L2CYP2D6HTR2AHTR2CKCNH2 | |
| SCHEMBL7107955 | 0.88 | CYP1A2 (0.52) | NFE2L2CYP1A2LMNACYP2D6MAPT | |
| SCHEMBL7107957 | 0.88 | CYP1A2 (0.52) | NFE2L2CYP1A2LMNACYP2D6MAPT | |
| SCHEMBL1194574 | 0.84 | MAPT (0.40) | NFE2L2KMT2ACYP1A2LMNAMEN1 | |
| SCHEMBL1194783 | 0.84 | MAOB (0.43) | NFE2L2CYP1A2MAPTHTTALDH1A1 | |
| SCHEMBL1194100 | 0.84 | MAPT (0.40) | NFE2L2KMT2ACYP1A2LMNAMEN1 | |
| SCHEMBL5872258 | 0.84 | TNFRSF1A (0.37) | NFE2L2CYP2D6HTR2AHTR2CKCNH2 | |
| SCHEMBL7736953 | 0.84 | MAOB (0.43) | NFE2L2CYP1A2MAPTHTTALDH1A1 | |
| SCHEMBL1195028 | 0.84 | NFE2L2 (0.55) | NFE2L2KMT2ALMNAMEN1MAPT | |
| SCHEMBL3668286 | 0.84 | MAOB (0.43) | NFE2L2CYP1A2MAPTHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1370253-B1 | USE OF ALPHA, BETA UNSATURATED ARYL SULFONES FOR PROTECTING CELLS AND TISSUES FROM IONIZING RADIATION TOXICITY | UNIV TEMPLE (US) | 2008-09-03 | — | — | EP | disclosed |