Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.36 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.33 |
| ▸ | STAT1 | P42224 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | RBBP9 | O75884 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9834300 | 0.85 | ALDH1A1 (0.42) | ALDH1A1NPC1RAB9APPARGNCOR2 | |
| SCHEMBL3069954 | 0.74 | METAP1 (0.36) | ALDH1A1FFAR2NR3C1TRPM8MEN1 | |
| SCHEMBL2936251 | 0.74 | FFAR2 (0.49) | ALDH1A1NPC1RAB9APPARGNCOR2 | |
| SCHEMBL27591332 | 0.74 | ALDH1A1 (0.44) | ALDH1A1NPC1RAB9APPARGNCOR2 | |
| SCHEMBL1428355 | 0.74 | FFAR2 (0.43) | ALDH1A1NPC1RAB9APPARGNCOR2 | |
| SCHEMBL25629359 | 0.72 | FFAR2 (0.45) | ALDH1A1NPC1RAB9APPARGNCOR2 | |
| SCHEMBL18764698 | 0.71 | ALDH1A1 (0.41) | ALDH1A1RAB9AHTTFFAR2SMN1; SMN2 | |
| SCHEMBL27600811 | 0.71 | ALDH1A1 (0.39) | ALDH1A1NPC1RAB9APPARGNCOR2 | |
| SCHEMBL14591145 | 0.71 | FFAR2 (0.49) | ALDH1A1NPC1RAB9APPARGNCOR2 | |
| SCHEMBL7320406 | 0.69 | ALDH1A1 (0.47) | ALDH1A1NPC1RAB9APPARGNCOR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1963315-A2 | ENZYME INHIBITORS | The Institute of Cancer Research (GB) | 2008-09-03 | — | — | EP | disclosed |
| WO-2007072017-A2 | ENZYME INHIBITORS | THE INSTITUTE OF CANCER RESEARCH (GB) | 2007-06-28 | — | — | WO | disclosed |