SCHEMBL5075381

SCHEMBL5075381

C[C@@]1(n2ccc(=O)[nH]c2=O)O[C@H](CO)[C@@H](O)[C@@]1(C)O

nearest known ligand 0.45

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
SLC28A1 O00337 1/20 0.45
SLC28A2 O43868 1/20 0.45
SLC29A1 Q99808 1/20 0.45
SLC28A3 Q9HAS3 1/20 0.45
P2RY14 Q15391 2/20 0.36
P2RY2 P41231 4/20 0.36
P2RY4 P51582 3/20 0.36
P2RY6 Q15077 6/20 0.35
CRBN Q96SW2 1/20 0.34
DUT P33316 3/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30974580 0.90 SLC28A1 (0.45) SLC28A1SLC28A2SLC29A1SLC28A3P2RY14
SCHEMBL28006945 0.88 SLC28A1 (0.43) SLC28A1SLC28A2SLC29A1SLC28A3P2RY14
SCHEMBL19303444 0.86 SLC28A1 (0.44) SLC28A1SLC28A2SLC29A1SLC28A3P2RY14
SCHEMBL27979205 0.86 SLC28A1 (0.44) SLC28A1SLC28A2SLC29A1SLC28A3P2RY14
SCHEMBL19223345 0.86 SLC28A1 (0.44) SLC28A1SLC28A2SLC29A1SLC28A3P2RY14
SCHEMBL31192375 0.85 SLC28A1 (0.42) SLC28A1SLC28A2SLC29A1SLC28A3P2RY14
SCHEMBL29084627 0.85 SLC28A1 (0.42) SLC28A1SLC28A2SLC29A1SLC28A3P2RY14
SCHEMBL28036977 0.85 SLC28A1 (0.43) SLC28A1SLC28A2SLC29A1SLC28A3P2RY14
SCHEMBL11266890 0.85 SLC28A1 (0.43) SLC28A1SLC28A2SLC29A1SLC28A3P2RY14
SCHEMBL30729687 0.84 SLC28A1 (0.41) SLC28A1SLC28A2SLC29A1SLC28A3P2RY14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 136 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024075022-A2 RNA CONSTRUCTS AND USES THEREOF BioNTech SE (DE) 2024-04-11 WO claimed
WO-2023215498-A2 COMPOSITIONS AND METHODS FOR CD28 ANTAGONISM MODERNATX, INC. (US) 2023-11-09 WO claimed
WO-2023166314-A2 RNA MOLECULE IMPERIAL COLLEGE INNOVATIONS LIMITED (GB) 2023-09-07 WO claimed
WO-2023052531-A1 TREATMENT INVOLVING NON-IMMUNOGENIC RNA FOR ANTIGEN VACCINATION AND PD-1 AXIS BINDING ANTAGONISTS BioNTech SE (DE) 2023-04-06 WO claimed
WO-2023051926-A1 TREATMENT INVOLVING NON-IMMUNOGENIC RNA FOR ANTIGEN VACCINATION AND PD-1 AXIS BINDING ANTAGONISTS BioNTech SE (DE) 2023-04-06 WO claimed
US-20260137803-A1 LIPID NANOPARTICLES AND METHODS OF MANUFACTURE AND USE THEREOF GENZYME CORP (US) 2026-05-21 US disclosed
US-20250281596-A1 IONIZABLE CATIONIC COMPOUND Seqirus Inc. 2025-09-11 US disclosed
WO-2025036992-A1 RNA CONJUGATES CureVac SE (DE) 2025-02-20 WO disclosed
WO-2024151685-A1 RECOMBINANT NUCLEIC ACID MOLECULES AND THEIR USE IN WOUND HEALING BETH ISRAEL DEACONESS MEDICAL CENTER, INC. (US) 2024-07-18 WO disclosed
WO-2024151673-A2 RECOMBINANT NUCLEIC ACID MOLECULES AND THEIR USE IN WOUND HEALING PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2024-07-18 WO disclosed
EP-4395901-A1 COMPOSITIONS AND METHODS FOR MODULATING KRAS EXPRESSION Molecular Axiom, LLC (US) 2024-07-10 EP disclosed
WO-2024133160-A1 HEPATITIS B COMPOSITIONS GLAXOSMITHKLINE BIOLOGICALS SA (BE) 2024-06-27 WO disclosed
US-20070229648-A1 EXPOSURE DEVICE AND IMAGE FORMING APPARATUS USING THE SAME MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 2007-10-04 US disclosed
EP-1576138-A2 2-BRANCHED NUCLEOSIDES AND FLAVIVIRIDAE MUTATION Idenix (Cayman) Limited (KY) 2005-09-21 EP disclosed
EP-1523489-A2 MODIFIED 2' AND 3' -NUCLEOSIDE PRODUGS FOR TREATING FLAVIRIDAE INFECTIONS Idenix (Cayman) Limited (KY) 2005-04-20 EP disclosed
EP-1263986-A4 PLATFORM FOR THE DISCOVERY OF THE BACTERIAL GENES INVOLVED IN RNA MODIFICATION TAO BIOSCIENCES LLC (US) 2005-02-23 EP disclosed
WO-2004046331-A2 2’-BRANCHED NUCLEOSIDES AND FLAVIVIRIDAE MUTATION IDENIX (CAYMAN) LIMITED (KY) 2004-06-03 WO disclosed
WO-2004002999-A2 MODIFIED 2' AND 3' -NUCLEOSIDE PRODUGS FOR TREATING FLAVIRIDAE INFECTIONS IDENIX (CAYMAN) LIMITED (KY) 2004-01-08 WO disclosed
EP-1263986-A1 PLATFORM FOR THE DISCOVERY OF THE BACTERIAL GENES INVOLVED IN RNA MODIFICATION Montclair Group (US) 2002-12-11 EP disclosed
WO-2001062981-A1 PLATFORM FOR THE DISCOVERY OF THE BACTERIAL GENES INVOLVED IN RNA MODIFICATION MONTCLAIR GROUP (US) 2001-08-30 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250281596-A1 IONIZABLE CATIONIC COMPOUND SLC11A2, ABCB4, ARG2 SLC28A1 467/4885SLC28A2 415/4885SLC29A1 190/4885
US-20260137803-A1 LIPID NANOPARTICLES AND METHODS OF MANUFACTURE AND USE THEREOF CD2BP2, CD2, CD4 SLC28A1 2826/4885SLC28A2 2444/4885SLC29A1 1701/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.