SCHEMBL5075498

SCHEMBL5075498

CC(SOS(=O)(=O)O)c1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.42
ALDH1A1 P00352 2/20 0.42
MAPT P10636 2/20 0.42
KDM4E B2RXH2 2/20 0.42
LMNA P02545 2/20 0.42
GMNN O75496 1/20 0.42
POLB P06746 1/20 0.42
HPGD P15428 1/20 0.42
PMP22 Q01453 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
SRC P12931 1/20 0.40
DAO P14920 2/20 0.36
MEN1 O00255 1/20 0.35
CYP2D6 P10635 1/20 0.35
MAPK1 P28482 1/20 0.35
TSHR P16473 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
ADRA2A P08913 1/20 0.34
ADRA2C P18825 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9861793 0.81 SRC (0.42) KMT2AALDH1A1MAPTKDM4ELMNA
SCHEMBL3248066 0.77 ALDH1A1 (0.42) KMT2AALDH1A1MAPTKDM4EPOLB
SCHEMBL913100 0.73 KMT2A (0.41) KMT2AALDH1A1KDM4ELMNACYP2D6
SCHEMBL8768557 0.73 KMT2A (0.42) KMT2AALDH1A1MAPTLMNASRC
Ammonia Solution, Strong SCHEMBL7105727 0.73 SRC (0.36) KMT2AALDH1A1MAPTKDM4ELMNA
SCHEMBL30295822 0.72 CYP3A4 (0.43) KMT2AALDH1A1MAPTLMNAHPGD
SCHEMBL776266 0.71 KMT2A (0.46) KMT2AALDH1A1MAPTKDM4ELMNA
Isopropylbenzene SCHEMBL27465893 0.71 KMT2A (0.46) KMT2AALDH1A1MAPTKDM4ELMNA
Sulfuric Acid SCHEMBL28371934 0.69 ALDH1A1 (0.57) KMT2AALDH1A1MAPTKDM4ELMNA
Isopropylbenzene SCHEMBL894807 0.69 ALDH1A1 (0.57) KMT2AALDH1A1MAPTKDM4ELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7417084-B2 Rubber compound containing an organothiosulfate and a bismaleimide THE GOODYEAR TIRE & RUBBER COMPANY (US) 2008-08-26 US claimed
EP-1674292-A1 Rubber compound containing an organothiosulfate and a bismaleimide THE GOODYEAR TIRE & RUBBER COMPANY (US) 2006-06-28 EP claimed
US-20060135660-A1 Rubber compound containing an organothiosulfate and a bismaleimide THE GOODYEAR TIRE & RUBBER COMPANY 2006-06-22 US claimed
US-7417084-B2 Rubber compound containing an organothiosulfate and a bismaleimide THE GOODYEAR TIRE & RUBBER COMPANY (US) 2008-08-26 US disclosed
EP-1674292-A1 Rubber compound containing an organothiosulfate and a bismaleimide THE GOODYEAR TIRE & RUBBER COMPANY (US) 2006-06-28 EP disclosed
US-20060135660-A1 Rubber compound containing an organothiosulfate and a bismaleimide THE GOODYEAR TIRE & RUBBER COMPANY 2006-06-22 US disclosed
EP-0109955-B1 RUBBER/METAL COMPOSITES MONSANTO EUROPE S.A./N.V. (BE) 1988-01-20 EP disclosed
US-4704334-A ORGANIC THIOSULFATE ADHESION PROMOTERS MONSANTO EUROPE, S.A. (BE) 1987-11-03 US disclosed
US-4532080-A Cobalt or nickel salt of organic thiosulfate ester MONSANTO EUROPE, S.A. (BE) 1985-07-30 US disclosed
EP-0109955-A2 Rubber/metal composites MONSANTO EUROPE S.A./N.V. (BE) 1984-05-30 EP disclosed