Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | DAO | P14920 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30295822 | 0.86 | CYP3A4 (0.43) | KMT2ACYP2D6SRCHCAR2ALOX5 | |
| SCHEMBL7403222 | 0.80 | KMT2A (0.41) | KMT2ALMNAMAPTMMP8ALDH1A1 | |
| SCHEMBL913100 | 0.76 | KMT2A (0.41) | KMT2ACYP2D6LMNAALDH1A1CYP3A4 | |
| SCHEMBL5075498 | 0.73 | KMT2A (0.42) | KMT2ACYP2D6SRCHCAR2LMNA | |
| SCHEMBL1959777 | 0.71 | TSHR (0.46) | KMT2ACYP2D6SRCALOX5LMNA | |
| SCHEMBL9864220 | 0.71 | ALOX5 (0.42) | KMT2ACYP2D6HCAR2ALOX5LMNA | |
| SCHEMBL6953010 | 0.69 | CYP2D6 (0.46) | CYP2D6SRCALOX5LMNAMAPK1 | |
| SCHEMBL28340407 | 0.69 | CYP2D6 (0.41) | KMT2ACYP2D6SRCALOX5LMNA | |
| SCHEMBL12276770 | 0.69 | KMT2A (0.34) | KMT2ACYP2D6HCAR2LMNADAO | |
| SCHEMBL24302355 | 0.69 | ADRA2C (0.44) | KMT2ACYP2D6LMNADAOALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0633241-B1 | Process for purifying diaryl carbonates | GEN ELECTRIC (US) | 1997-09-10 | — | — | EP | disclosed |