SCHEMBL5075502

SCHEMBL5075502

Cc1c(N2C(=O)C=CC2=O)ccc(N2C(=O)C=CC2=O)c1C

nearest known ligand 0.58

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ MGLL Q99685 15/20 0.58
▸ TLR9 Q9NR96 2/20 0.56
▸ FAAH O00519 3/20 0.48
▸ G6PD P11413 1/20 0.47
▸ HSP90AA1 P07900 3/20 0.44
▸ CCR6 P51684 2/20 0.44
▸ ALDH1A1 P00352 1/20 0.42
▸ MAPT P10636 1/20 0.42
▸ PKM P14618 1/20 0.42
▸ HPGD P15428 1/20 0.42
▸ HTT P42858 1/20 0.42
▸ NPSR1 Q6W5P4 1/20 0.42
▸ NLRP1 Q9C000 1/20 0.42
▸ TDP1 Q9NUW8 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29757193 1.00 MGLL (0.58) MGLLTLR9FAAHG6PDHSP90AA1
SCHEMBL7607386 0.91 MGLL (0.55) MGLLTLR9FAAHG6PDHSP90AA1
SCHEMBL30673728 0.87 MGLL (0.47) MGLLTLR9FAAHG6PDHSP90AA1
SCHEMBL144793 0.85 MGLL (0.65) MGLLTLR9FAAHHSP90AA1CCR6
SCHEMBL9418760 0.83 MGLL (0.52) MGLLTLR9FAAHG6PDHSP90AA1
SCHEMBL29440938 0.80 MGLL (0.70) MGLLTLR9FAAHHSP90AA1ALDH1A1
SCHEMBL710771 0.80 MGLL (0.70) MGLLTLR9FAAHHSP90AA1ALDH1A1
SCHEMBL28884028 0.78 MGLL (0.52) MGLLTLR9FAAHG6PDHSP90AA1
SCHEMBL9067561 0.77 TLR9 (0.54) MGLLTLR9FAAHG6PDHSP90AA1
SCHEMBL9172497 0.77 MGLL (0.66) MGLLTLR9FAAHHSP90AA1CCR6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5300585-A Having improved cure reversion THE GOODYEAR TIRE & RUBBER COMPANY (US) 1994-04-05 — — US claimed
US-12552908-B2 Thermally expandable compositions comprising a chemical blowing agent SIKA TECHNOLOGY AG (CH) 2026-02-17 — — US disclosed
US-20220372238-A1 THERMALLY EXPANDABLE COMPOSITIONS COMPRISING A CHEMICAL BLOWING AGENT SIKA TECHNOLOGY AG (CH) 2022-11-24 — — US disclosed
EP-4039733-A1 METHODS FOR CROSSLINKING POLYMER COMPOSITIONS IN THE PRESENCE OF ATMOSPHERIC OXYGEN Arkema, Inc. (US) 2022-08-10 — — EP disclosed
EP-4013810-A1 THERMALLY EXPANDABLE COMPOSITIONS COMPRISING A CHEMICAL BLOWING AGENT Sika Technology AG (CH) 2022-06-22 — — EP disclosed
US-20220112373-A1 THERMOSETTING RESIN COMPOSITION SHOWA DENKO K.K. (JP) 2022-04-14 — — US disclosed
CN-109689742-B Curable resin mixture and method for producing curable resin composition 昭和电工株式会社 2021-12-10 — — CN disclosed
EP-2970605-B1 METHODS FOR CROSSLINKING POLYMER COMPOSITIONS IN THE PRESENCE OF ATMOSPHERIC OXYGEN ARKEMA INC (US) 2021-12-01 — — EP disclosed
US-20210284783-A1 METHODS FOR PRODUCING CURABLE RESIN MIXTURE AND CURABLE RESIN COMPOSITION SHOWA DENKO K.K. (JP) 2021-09-16 — — US disclosed
CN-113316597-A Thermosetting resin composition 昭和电工株式会社 2021-08-27 — — CN disclosed
US-5262488-A Rubber for aging, tear resistance and tensile strength THE GOODYEAR TIRE & RUBBER COMPANY (US) 1993-11-16 — — US disclosed
EP-0564966-A2 A rubber vulcanization composition THE GOODYEAR TIRE & RUBBER COMPANY (US) 1993-10-13 — — EP disclosed
EP-0345825-B1 RUBBER COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-08-11 — — EP disclosed
US-5109055-A Blend with a dinitrodiamine compound with n-(cyclohexylthio)-phthalimide and(or) 2,3,5,6-tetrachloro-1,4-benzoqionone SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1992-04-28 — — US disclosed
EP-0410152-A1 Rubber composition having excellent dynamic properties SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1991-01-30 — — EP disclosed
US-4960833-A Rubber composition with nitrogen and phosphorous compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1990-10-02 — — US disclosed
EP-0191931-B1 RUBBER COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1990-07-04 — — EP disclosed
EP-0345825-A1 Rubber composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1989-12-13 — — EP disclosed
US-4803250-A AROMATIC CARBOXYLIC ANHYDRIDE, BISMALEIMIDE, SULFUR, ACCELERATOR, NONREVERTING, ANTICRACKING SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1989-02-07 — — US disclosed
EP-0191931-A2 Rubber composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1986-08-27 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12552908-B2 Thermally expandable compositions comprising a chemical blowing agent CA1, CA3, CA12 MGLL 2570/4885TLR9 2893/4885FAAH 462/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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