SCHEMBL5075918

SCHEMBL5075918

CO/C=C(/C(=O)O)c1ccccc1COc1cc(Cl)c(OCc2ccc(Cl)cc2Cl)c(Cl)c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FABP3 P05413 1/20 0.49
FABP4 P15090 1/20 0.49
FABP5 Q01469 1/20 0.49
MRGPRX4 Q96LA9 3/20 0.47
NR4A2 P43354 2/20 0.46
NR4A1 P22736 1/20 0.46
NR4A3 Q92570 1/20 0.46
SMN1; SMN2 Q16637 2/20 0.41
ALDH1A1 P00352 1/20 0.41
MAPT P10636 1/20 0.41
NCOA1 Q15788 1/20 0.41
NCOA3 Q9Y6Q9 1/20 0.41
FFAR1 O14842 5/20 0.41
S1PR1 P21453 1/20 0.41
LTK P29376 1/20 0.41
TAOK1 Q7L7X3 1/20 0.41
S1PR5 Q9H228 1/20 0.41
KMT2A Q03164 2/20 0.40
PPARG P37231 1/20 0.40
SLC26A4 O43511 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5075928 1.00 FABP3 (0.49) FABP3FABP4FABP5MRGPRX4NR4A2
SCHEMBL5075922 0.91 FABP3 (0.52) FABP3FABP4FABP5MRGPRX4NR4A2
SCHEMBL5075956 0.90 HIF1A (0.48) MRGPRX4NR4A2MAPTFFAR1
SCHEMBL5075957 0.90 HIF1A (0.48) MRGPRX4NR4A2MAPTFFAR1
SCHEMBL6151249 0.89 HIF1A (0.44) MRGPRX4SMN1; SMN2ALDH1A1S1PR1S1PR5
SCHEMBL6151245 0.89 HIF1A (0.44) MRGPRX4SMN1; SMN2ALDH1A1S1PR1S1PR5
SCHEMBL5075979 0.88 RAB9A (0.46) MRGPRX4NR4A2SMN1; SMN2ALDH1A1MAPT
SCHEMBL5075974 0.88 RAB9A (0.46) MRGPRX4NR4A2SMN1; SMN2ALDH1A1MAPT
SCHEMBL5079482 0.87 MRGPRX4 (0.44) MRGPRX4NR4A2ALDH1A1KMT2AMEN1
SCHEMBL5079484 0.87 MRGPRX4 (0.44) MRGPRX4NR4A2ALDH1A1KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7435844-B2 Analogous compounds of strobilurines and their use as acaricides and insecticides ISAGRO RICERCA S.R.L. (IT) 2008-10-14 US claimed
US-20060235075-A1 Analogous compounds of strobilurines and their use as acaricides and insecticides ISAGRO RICERCA S.R.L. (IT) 2006-10-19 US claimed
EP-1494991-A1 ANALOGOUS COMPOUNDS OF STROBILURINES AND THEIR USE AS ACARICIDES AND INSECTICIDES Isagro Ricerca S.r.l. (IT) 2005-01-12 EP claimed
WO-2003087032-A1 ANALOGOUS COMPOUNDS OF STROBILURINES AND THEIR USE AS ACARICIDES AND INSECTICIDES ISAGRO RICERCA S.R.L. (IT) 2003-10-23 WO claimed
US-7435844-B2 Analogous compounds of strobilurines and their use as acaricides and insecticides ISAGRO RICERCA S.R.L. (IT) 2008-10-14 US disclosed
US-20060235075-A1 Analogous compounds of strobilurines and their use as acaricides and insecticides ISAGRO RICERCA S.R.L. (IT) 2006-10-19 US disclosed
EP-1494991-A1 ANALOGOUS COMPOUNDS OF STROBILURINES AND THEIR USE AS ACARICIDES AND INSECTICIDES Isagro Ricerca S.r.l. (IT) 2005-01-12 EP disclosed
WO-2003087032-A1 ANALOGOUS COMPOUNDS OF STROBILURINES AND THEIR USE AS ACARICIDES AND INSECTICIDES ISAGRO RICERCA S.R.L. (IT) 2003-10-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060235075-A1 Analogous compounds of strobilurines and their use as acaricides and insecticides DDT, RYR1, TPMT FABP3 4004/4885FABP4 2057/4885FABP5 2502/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.