SCHEMBL6151245

SCHEMBL6151245

CO/C=C(/C(=O)O)c1ccccc1COc1cc(Cl)c(OCc2ccccc2)c(Cl)c1

nearest known ligand 0.49

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 2/20 0.44
LMNA P02545 2/20 0.41
ALDH1A1 P00352 1/20 0.41
S1PR1 P21453 1/20 0.41
PRKX P51817 1/20 0.41
ACVR1 Q04771 1/20 0.41
S1PR5 Q9H228 1/20 0.41
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
NPC1 O15118 1/20 0.40
RAB9A P51151 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
KDM4E B2RXH2 1/20 0.40
TP53 P04637 1/20 0.39
HTT P42858 1/20 0.39
MRGPRX4 Q96LA9 1/20 0.39
HPGD P15428 1/20 0.39
MAOB P27338 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6151249 1.00 HIF1A (0.44) HIF1ALMNAALDH1A1S1PR1PRKX
SCHEMBL5075957 0.95 HIF1A (0.48) HIF1ALMNAMRGPRX4MAOB
SCHEMBL5075956 0.95 HIF1A (0.48) HIF1ALMNAMRGPRX4MAOB
SCHEMBL6150392 0.94 FFAR1 (0.41) HIF1AALDH1A1S1PR1PRKXACVR1
SCHEMBL6150393 0.94 FFAR1 (0.41) HIF1AALDH1A1S1PR1PRKXACVR1
SCHEMBL5075841 0.92 HIF1A (0.50) HIF1ALMNAALDH1A1S1PR1PRKX
SCHEMBL5075979 0.90 RAB9A (0.46) HIF1ALMNAALDH1A1MEN1KMT2A
SCHEMBL5075974 0.90 RAB9A (0.46) HIF1ALMNAALDH1A1MEN1KMT2A
SCHEMBL6151247 0.90 HIF1A (0.44) HIF1ALMNAALDH1A1S1PR1PRKX
SCHEMBL5079482 0.90 MRGPRX4 (0.44) HIF1ALMNAALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1494991-A1 ANALOGOUS COMPOUNDS OF STROBILURINES AND THEIR USE AS ACARICIDES AND INSECTICIDES Isagro Ricerca S.r.l. (IT) 2005-01-12 EP disclosed
WO-2003087032-A1 ANALOGOUS COMPOUNDS OF STROBILURINES AND THEIR USE AS ACARICIDES AND INSECTICIDES ISAGRO RICERCA S.R.L. (IT) 2003-10-23 WO disclosed