SCHEMBL507594

SCHEMBL507594

Nc1ccc(N=C=Nc2ccc(N)cc2)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.55
TDP1 Q9NUW8 5/20 0.55
MEN1 O00255 3/20 0.55
KMT2A Q03164 3/20 0.55
RAB9A P51151 3/20 0.55
L3MBTL1 Q9Y468 2/20 0.55
NPC1 O15118 2/20 0.55
SMN1; SMN2 Q16637 1/20 0.55
KDM4E B2RXH2 1/20 0.46
POLB P06746 1/20 0.46
GAA P10253 1/20 0.46
PKM P14618 1/20 0.46
HTT P42858 1/20 0.46
NOS3 P29474 1/20 0.42
NOS1 P29475 1/20 0.42
NOS2 P35228 1/20 0.42
APP P05067 2/20 0.41
ALDH1A1 P00352 5/20 0.40
CYP3A4 P08684 5/20 0.40
TP53 P04637 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15485541 0.78 MAPT (0.50) MAPTTDP1MEN1KMT2ARAB9A
SCHEMBL6815770 0.78 MIF (0.56) MAPTTDP1MEN1KMT2ARAB9A
SCHEMBL6507762 0.78 CYP3A4 (0.56) MAPTTDP1MEN1KMT2ARAB9A
SCHEMBL6942015 0.73
SCHEMBL20108074 0.72 TDP1 (0.50) MAPTTDP1MEN1KMT2ARAB9A
SCHEMBL3507432 0.72 MAPT (0.64) MAPTTDP1MEN1KMT2ARAB9A
SCHEMBL3507431 0.72 MAPT (0.64) MAPTTDP1MEN1KMT2ARAB9A
SCHEMBL11329226 0.71 MAPT (1.00) MAPTTDP1MEN1KMT2ARAB9A
SCHEMBL16556 0.71 MAPT (1.00) MAPTTDP1MEN1KMT2ARAB9A
SCHEMBL11329248 0.71 MAPT (1.00) MAPTTDP1MEN1KMT2ARAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 416 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180134947-A1 METHODS FOR TREATING HIGH TEMPERATURE SUBTERRANEAN FORMATIONS SCHLUMBERGER TECHNOLOGY CORPORATION 2018-05-17 US claimed
WO-2016159817-A1 METHODS FOR TREATING HIGH TEMPERATURE SUBTERRANEAN FORMATIONS SCHLUMBERGER CANADA LIMITED (CA) 2016-10-06 WO claimed
EP-2270606-B1 ELECTROCONDUCTIVE ENDLESS BELT BRIDGESTONE CORP (JP) 2013-07-10 EP claimed
US-20120329910-A1 Thermoplastic Resin Composition and Molded Product Using the Same CHEIL INDUSTRIES INC. (KR) 2012-12-27 US claimed
US-20110033205-A1 ELECTROCONDUCTIVE ENDLESS BELT BRIDGESTONE CORPORATION (JP) 2011-02-10 US claimed
EP-2270606-A1 ELECTROCONDUCTIVE ENDLESS BELT Bridgestone Corporation (JP) 2011-01-05 EP claimed
US-12559624-B2 Film comprising polylactic acid polymer suitable for graphic articles 3M INNOVATIVE PROPERTIES COMPANY (US) 2026-02-24 US disclosed
EP-4516835-A1 SEMI-AROMATIC POLYESTER, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF Zhuhai Kingfa Biomaterial Co., Ltd. (CN) 2025-03-05 EP disclosed
US-20240294748-A1 FILM COMPRISING POLYLACTIC ACID POLYMER SUITABLE FOR GRAPHIC ARTICLES 3M INNOVATIVE PROPERTIES COMPANY (US) 2024-09-05 US disclosed
US-12065531-B2 Polyglycolic acid resin and production process thereof PUJING CHEMICAL INDUSTRY CO., LTD. (CN) 2024-08-20 US disclosed
EP-4400527-A1 SEMI-AROMATIC POLYESTER, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF Zhuhai Wango Chemical Co., Ltd. (CN) 2024-07-17 EP disclosed
EP-4400529-A1 SEMI-AROMATIC POLYETHER ESTER, PREPARATION METHOD THEREFOR AND USE THEREOF Zhuhai Wango Chemical Co., Ltd. (CN) 2024-07-17 EP disclosed
EP-4400530-A1 POLYESTER, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF Zhuhai Wango Chemical Co., Ltd. (CN) 2024-07-17 EP disclosed
US-5886088-A A BLENDS OF MOLDING MATERIAL COMPRISING AN EPOXY COMPOUND OR RESIN AND A POLYFUNCTIONAL CARBODIIMIDE COMPOUND TO IMPROVE THE MOIST HEAT RESISTANCE, FLUIDITY AND MECHANICAL STRENGTH KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1999-03-23 US disclosed
US-5866672-A HALOGEN FLAME RETARDANT, EPOXY COMPOUNDS OR CARBODIIMIDE COMPOUNDS AND AN ANTIMONY COMPOUND KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1999-02-02 US disclosed
US-5686552-A Polyester compositions, polyester monofilaments; process for production thereof and products employing polyester monofilaments TORAY INDUSTRIES, INC. (JP) 1997-11-11 US disclosed
EP-0763567-A1 FLAME-RETARDANT POLYETHYLENE TEREPHTHALATE RESIN COMPOSITIONS Kanegafuchi Kagaku Kogyo Kabushiki Kaisha (JP) 1997-03-19 EP disclosed
US-5378537-A Polyester monofilament TORAY INDUSTRIES, INC. (JP) 1995-01-03 US disclosed
EP-0506983-A1 POLYESTER MONOFILAMENT TORAY INDUSTRIES, INC. (JP) 1992-10-07 EP disclosed
US-3975329-A HYDROLYTIC AND THERMAL STABILITY THE GOODYEAR TIRE & RUBBER COMPANY (US) 1976-08-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12065531-B2 Polyglycolic acid resin and production process thereof RPN2, RIOX2, RPN1 MAPT 535/4885TDP1 3501/4885MEN1 4599/4885
US-12559624-B2 Film comprising polylactic acid polymer suitable for graphic articles POT1, PARG, TCP1 MAPT 209/4885TDP1 6/4885MEN1 580/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.