SCHEMBL5076822

SCHEMBL5076822

O=C(O)Cc1ccccc1CCc1ccccc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1B1 P15121 2/20 0.58
FFAR1 O14842 1/20 0.55
KEAP1 Q14145 1/20 0.54
HDAC1 Q13547 3/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
ALDH1A1 P00352 2/20 0.50
HDAC3 O15379 1/20 0.50
MAPK1 P28482 1/20 0.50
ADRA1A P35348 1/20 0.50
HDAC4 P56524 1/20 0.50
SLC6A3 Q01959 1/20 0.50
HDAC7 Q8WUI4 1/20 0.50
HDAC2 Q92769 1/20 0.50
HDAC10 Q969S8 1/20 0.50
HDAC11 Q96DB2 1/20 0.50
HDAC8 Q9BY41 1/20 0.50
HDAC6 Q9UBN7 1/20 0.50
HDAC9 Q9UKV0 1/20 0.50
HDAC5 Q9UQL6 1/20 0.50
ADRB2 P07550 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24661354 1.00 AKR1B1 (0.58) AKR1B1FFAR1KEAP1HDAC1SMN1; SMN2
SCHEMBL29652140 0.92 AKR1B1 (0.59) AKR1B1FFAR1KEAP1SMN1; SMN2ALDH1A1
SCHEMBL8108320 0.88 HDAC1 (0.57) AKR1B1FFAR1KEAP1HDAC1SMN1; SMN2
SCHEMBL28705033 0.85 AKR1B1 (0.50) AKR1B1FFAR1KEAP1HDAC1SMN1; SMN2
SCHEMBL30335940 0.85 AKR1B1 (0.55) AKR1B1FFAR1KEAP1HDAC1SMN1; SMN2
SCHEMBL30359 0.84 AKR1B1 (0.76) AKR1B1ADRA1ATDP1LMNAKDM4E
SCHEMBL29410826 0.84 AKR1B1 (0.76) AKR1B1ADRA1ATDP1LMNAKDM4E
SCHEMBL28407102 0.83 AKR1B1 (0.53) AKR1B1FFAR1KEAP1HDAC1SMN1; SMN2
SCHEMBL9375792 0.82 HPGD (0.50) AKR1B1FFAR1KEAP1HDAC1SMN1; SMN2
Hydrochloric Acid SCHEMBL6767821 0.82 AKR1B1 (0.73) AKR1B1ADRA1ATDP1LMNAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120077502-A Electrolyte, electrochemical device, secondary battery, and lithium ion secondary battery 大金工业株式会社 2025-05-30 CN disclosed
CN-119422259-A Surface treatment agent for electrode material, positive electrode active material, current collecting foil, negative electrode active material, conductive auxiliary agent, electrode, battery, method for producing positive electrode active material, method for producing current collecting foil, method for producing negative electrode active material, method for producing conductive auxiliary agent, and method for producing electrode 大金工业株式会社 2025-02-11 CN disclosed
EP-4016044-B1 IMPROVED METHOD FOR OPTICALLY CLARIFYING A TISSUE SAMPLE FOR MICROSCOPIC EXAMINATION MobiCron GmbH (DE) 2025-02-05 EP disclosed
CN-119318048-A Electrolyte and secondary battery using the same 大金工业株式会社 2025-01-14 CN disclosed
CN-114730876-B Electrode and electrochemical device 大金工业株式会社 2024-09-27 CN disclosed
CN-111919326-B Electrolyte, electrochemical device, lithium ion secondary battery, assembly, and compound 大金工业株式会社 2024-06-11 CN disclosed
CN-118026845-A Fluoroacetate compound 大金工业株式会社 2024-05-14 CN disclosed
CN-111937215-B Electrolyte, electrochemical device, lithium ion secondary battery, and assembly 大金工业株式会社 2024-04-19 CN disclosed
CN-117865841-A Electrolyte, electrochemical device, lithium ion secondary battery and assembly 大金工业株式会社 2024-04-12 CN disclosed
CN-112042036-B Electrolyte, electrochemical device, lithium ion secondary battery, and assembly 大金工业株式会社 2024-03-05 CN disclosed
CN-110326150-B Nonaqueous electrolyte solution and electricity storage device 三菱化学株式会社 2022-05-03 CN disclosed
CN-114364776-A Detergent composition 联合利华知识产权控股有限公司 2022-04-15 CN disclosed
CN-114174584-A Fabric spray composition 联合利华知识产权控股有限公司 2022-03-11 CN disclosed
CN-110446724-B Surfactant responsive emulsion polymerization microgels 路博润先进材料公司 2021-11-05 CN disclosed
CN-111433577-B Temperature detection label and article management device using same 株式会社日立制作所 2021-09-21 CN disclosed
CN-111602041-A Temperature detection ink, method for initializing temperature detection ink, temperature indicator, and article management system 株式会社日立产机系统 2020-08-28 CN disclosed
CN-109154528-B Temperature history display body and article quality management method using same 株式会社日立制作所 2020-06-30 CN disclosed
US-7582667-B2 Dihydrospiro[dibenzo[a,d][7]annulene-5,4′-imidazol] compounds for the inhibition of beta-secretase WYETH (US) 2009-09-01 US disclosed
US-20080267939-A1 SYNERGISTIC ANTI-HYPERTENSIVE PHYTO-NUTRACEUTICAL COMPOSITION OLALDE RANGEL JOSE ANGEL 2008-10-30 US disclosed
US-20070203116-A1 Dihydrospiro[dibenzo[a,d][7]annulene-5,4'-imidazol] compounds for the inhibition of beta-secretase WYETH (US) 2007-08-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070203116-A1 Dihydrospiro[dibenzo[a,d][7]annulene-5,4'-imidazol] compounds for the inhibition of beta-secretase BACE1, BACE2, APP AKR1B1 763/4885FFAR1 3932/4885KEAP1 286/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.