Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.46 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.46 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.46 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.46 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16041940 | 0.84 | KEAP1 (0.54) | HPGDCXCL8CYP2C9CHRM1ALOX15 | |
| SCHEMBL5076822 | 0.82 | AKR1B1 (0.58) | MAPK1AKR1B1ALDH1A1LMNAHDAC3 | |
| SCHEMBL24661354 | 0.82 | AKR1B1 (0.58) | MAPK1AKR1B1ALDH1A1LMNAHDAC3 | |
| SCHEMBL23552455 | 0.81 | MRGPRX4 (0.54) | HPGDCXCL8CYP2C9CHRM1ALOX15 | |
| SCHEMBL574406 | 0.81 | ALOX15 (0.71) | HPGDCYP2C9ALOX15MAPK1MEN1 | |
| SCHEMBL9075274 | 0.79 | CHRM1 (0.52) | CHRM1MAPT | |
| SCHEMBL9077989 | 0.79 | CHRM1 (0.52) | CHRM1PTGDR2 | |
| SCHEMBL4608622 | 0.79 | MAPT (0.56) | HPGDCXCL8CYP2C9CHRM1ALOX15 | |
| SCHEMBL9078395 | 0.78 | CHRM1 (0.51) | CHRM1ALDH1A1LMNAPTGDR2L3MBTL1 | |
| SCHEMBL28407102 | 0.78 | AKR1B1 (0.53) | HPGDMAPK1HIF1AHSD17B10AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0286346-B1 | Insecticidal substituted indazoles | DU PONT (US) | 1994-04-06 | — | — | EP | disclosed |
| EP-0438458-A1 | SUBSTITUTED INDAZOLES AS ARTHROPODICIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-07-31 | — | — | EP | disclosed |
| US-4960784-A | Insecticidal substituted indazoles | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1990-10-02 | — | — | US | disclosed |
| EP-0365201-A1 | Substituted indazoles as arthropodicides | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1990-04-25 | — | — | EP | disclosed |
| WO-1990003969-A1 | SUBSTITUTED INDAZOLES AS ARTHROPODICIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1990-04-19 | — | — | WO | disclosed |
| EP-0362216-A1 | INSECTICIDAL SUBSTITUTED INDAZOLES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1990-04-11 | — | — | EP | disclosed |
| WO-1988007994-A1 | INSECTICIDAL SUBSTITUTED INDAZOLES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-10-20 | — | — | WO | disclosed |
| EP-0286346-A2 | Insecticidal substituted indazoles | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-10-12 | — | — | EP | disclosed |