⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5618482 | 0.63 | GAA (0.32) | — | |
| SCHEMBL1328632 | 0.60 | — | — | |
| SCHEMBL28199911 | 0.59 | — | — | |
| SCHEMBL3842390 | 0.59 | — | — | |
| SCHEMBL28152872 | 0.59 | — | — | |
| SCHEMBL1646118 | 0.59 | — | — | |
| SCHEMBL604100 | 0.59 | — | — | |
| SCHEMBL502946 | 0.59 | — | — | |
| SCHEMBL2711721 | 0.59 | — | — | |
| SCHEMBL21843292 | 0.59 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104470899-B | The 4 isoquinolinol compounds as HIF hydroxylase inhibitors | 菲布罗根有限公司 | 2017-12-26 | — | — | CN | claimed |
| CN-107266345-A | It is used as (miscellaneous) aryl rings propanamine compounds of LSD1 inhibitor | 奥瑞泽恩基因组学股份有限公司 | 2017-10-20 | — | — | CN | claimed |
| EP-2834220-A1 | 4 -HYDROXY- ISOQUINOLINE COMPOUNDS AS HIF HYDROXYLASE INHIBITORS | Fibrogen, Inc. (US) | 2015-02-11 | — | — | EP | claimed |
| WO-2013134660-A1 | 4 -HYDROXY- ISOQUINOLINE COMPOUNDS AS HIF HYDROXYLASE INHIBITORS | FIBROGEN, INC. (US) | 2013-09-12 | — | — | WO | claimed |
| US-20210289794-A1 | COMPOSITIONS AND RELATED METHODS FOR AGRICULTURE | FLAGSHIP PIONEERING INNOVATIONS V, INC. | 2021-09-23 | — | — | US | disclosed |
| CN-107266345-B | (hetero) arylcyclopropylamine compounds as LSD1 inhibitors | 奥瑞泽恩基因组学股份有限公司 | 2021-08-17 | — | — | CN | disclosed |
| EP-3736265-A1 | (HETERO)ARYL CYCLOPROPYLAMINE COMPOUNDS AS LSD1 INHIBITORS | Oryzon Genomics, S.A. (ES) | 2020-11-11 | — | — | EP | disclosed |
| EP-2768805-B1 | (HETERO)ARYL CYCLOPROPYLAMINE COMPOUNDS AS LSD1 INHIBITORS | ORYZON GENOMICS SA (ES) | 2020-03-25 | — | — | EP | disclosed |
| US-10329256-B2 | (Hetero)aryl cyclopropylamine compounds as LSD1 inhibitors | ORYZON GENOMICS, S.A. (ES) | 2019-06-25 | — | — | US | disclosed |
| US-20180354902-A1 | (HETERO)ARYL CYCLOPROPYLAMINE COMPOUNDS AS LSD1 INHIBITORS | ORYZON GENOMICS S.A. (ES) | 2018-12-13 | — | — | US | disclosed |
| CN-105209448-B | Tricyclic compounds and uses thereof | 株式会社蒂奥姆生物 | 2018-09-14 | — | — | CN | disclosed |
| EP-2895495-B1 | ISOXAZOLIDINE DERIVATIVES | CHIESI FARM SPA (IT) | 2018-05-16 | — | — | EP | disclosed |
| WO-2006136917-A1 | TRIAZOLYLPIPERIDINE DERIVATIVES AND USE THEREOF IN THERAPY | PFIZER LIMITED (GB) | 2006-12-28 | — | — | WO | disclosed |
| CN-1726201-A | Substituted piperazines, (1,4) diaza * class and 2, 5-diazabicyclo (2.2.1) heptanes as histamine H1 and/or H3 antagonists or histamine H3 reverse antagonists | GLAXO GROUP LTD (GB) | 2006-01-25 | — | — | CN | disclosed |
| CN-1181096-C | Cyclic hexapeptide somatostatin analogues | ����̫�¹�˾ | 2004-12-22 | — | — | CN | disclosed |
| CN-1065277-C | Process for production of avermectins and cultures therefor | PFIZER (US) | 2001-05-02 | — | — | CN | disclosed |
| CN-1056883-C | Process for production of B avermectins and cultures therefor | AMERICAN PIFZER INC (US) | 2000-09-27 | — | — | CN | disclosed |
| CN-1161698-A | Cyclic hexapeptide somatostatin analogues | DIATECH INC (US) | 1997-10-08 | — | — | CN | disclosed |
| CN-88100649-A | Methods for producing avermectin B and cultures thereof | — | 1988-10-26 | — | — | CN | disclosed |
| CN-88100373-A | Avermectins and production method of culture bacteria thereof | — | 1988-08-31 | — | — | CN | disclosed |