SCHEMBL5077491

SCHEMBL5077491

O=C1C=CC(=O)N1c1cc(O)cc(N2C(=O)C=CC2=O)c1

nearest known ligand 0.60

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 12/20 0.60
HSP90AA1 P07900 3/20 0.60
PKM P14618 1/20 0.60
MAPK1 P28482 1/20 0.60
NPSR1 Q6W5P4 1/20 0.60
TDP1 Q9NUW8 1/20 0.60
NSD2 O96028 1/20 0.59
G6PD P11413 1/20 0.59
KEAP1 Q14145 1/20 0.59
NFE2L2 Q16236 1/20 0.59
FAAH O00519 6/20 0.56
CCR6 P51684 2/20 0.54
DDAH1 O94760 1/20 0.43
BCHE P06276 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8641616 0.87 MGLL (0.70) MGLLHSP90AA1PKMMAPK1NPSR1
SCHEMBL27558844 0.85 MGLL (0.53) MGLLHSP90AA1PKMMAPK1NPSR1
SCHEMBL27558828 0.80 MGLL (0.46) MGLLHSP90AA1PKMMAPK1NPSR1
SCHEMBL139055 0.78 MGLL (0.72) MGLLHSP90AA1PKMMAPK1NPSR1
SCHEMBL27491984 0.78 MGLL (0.72) MGLLHSP90AA1PKMMAPK1NPSR1
SCHEMBL29510527 0.78 MGLL (0.72) MGLLHSP90AA1PKMMAPK1NPSR1
SCHEMBL5078820 0.77 MGLL (0.62) MGLLHSP90AA1PKMMAPK1NPSR1
SCHEMBL24702071 0.75 MGLL (0.63) MGLLHSP90AA1PKMMAPK1NPSR1
SCHEMBL140288 0.75 MGLL (1.00) MGLLHSP90AA1PKMMAPK1NPSR1
SCHEMBL144792 0.75 HSP90AA1 (0.91) MGLLHSP90AA1NPSR1NSD2G6PD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12552908-B2 Thermally expandable compositions comprising a chemical blowing agent SIKA TECHNOLOGY AG (CH) 2026-02-17 US disclosed
CN-118772377-A Urea epoxy curing accelerator, epoxy conductive silver adhesive and preparation method 汉方新材料科技(嘉善)有限公司 2024-10-15 CN disclosed
US-11753522-B2 Use of magnesium oxide for crosslinking polymers ARKEMA FRANCE (FR) 2023-09-12 US disclosed
US-20220372238-A1 THERMALLY EXPANDABLE COMPOSITIONS COMPRISING A CHEMICAL BLOWING AGENT SIKA TECHNOLOGY AG (CH) 2022-11-24 US disclosed
EP-4039733-A1 METHODS FOR CROSSLINKING POLYMER COMPOSITIONS IN THE PRESENCE OF ATMOSPHERIC OXYGEN Arkema, Inc. (US) 2022-08-10 EP disclosed
EP-4013810-A1 THERMALLY EXPANDABLE COMPOSITIONS COMPRISING A CHEMICAL BLOWING AGENT Sika Technology AG (CH) 2022-06-22 EP disclosed
EP-2970605-B1 METHODS FOR CROSSLINKING POLYMER COMPOSITIONS IN THE PRESENCE OF ATMOSPHERIC OXYGEN ARKEMA INC (US) 2021-12-01 EP disclosed
WO-2021028599-A1 THERMALLY EXPANDABLE COMPOSITIONS COMPRISING A CHEMICAL BLOWING AGENT SIKA TECHNOLOGY AG (CH) 2021-02-18 WO disclosed
EP-3778734-A1 THERMALLY EXPANDABLE COMPOSITIONS COMPRISING A CHEMICAL BLOWING AGENT SIKA TECHNOLOGY AG (CH) 2021-02-17 EP disclosed
EP-2780413-B1 NANOSILICA CONTAINING POLYCYANATE ESTER RESIN COMPOSITIONS 3M INNOVATIVE PROPERTIES CO (US) 2019-09-25 EP disclosed
US-5262488-A Rubber for aging, tear resistance and tensile strength THE GOODYEAR TIRE & RUBBER COMPANY (US) 1993-11-16 US disclosed
EP-0564966-A2 A rubber vulcanization composition THE GOODYEAR TIRE & RUBBER COMPANY (US) 1993-10-13 EP disclosed
EP-0345825-B1 RUBBER COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-08-11 EP disclosed
US-5109055-A Blend with a dinitrodiamine compound with n-(cyclohexylthio)-phthalimide and(or) 2,3,5,6-tetrachloro-1,4-benzoqionone SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1992-04-28 US disclosed
EP-0410152-A1 Rubber composition having excellent dynamic properties SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1991-01-30 EP disclosed
US-4960833-A Rubber composition with nitrogen and phosphorous compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1990-10-02 US disclosed
EP-0191931-B1 RUBBER COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1990-07-04 EP disclosed
EP-0345825-A1 Rubber composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1989-12-13 EP disclosed
US-4803250-A AROMATIC CARBOXYLIC ANHYDRIDE, BISMALEIMIDE, SULFUR, ACCELERATOR, NONREVERTING, ANTICRACKING SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1989-02-07 US disclosed
EP-0191931-A2 Rubber composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1986-08-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12552908-B2 Thermally expandable compositions comprising a chemical blowing agent CA1, CA3, CA12 MGLL 2570/4885HSP90AA1 946/4885PKM 4160/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.