Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 4/20 | 0.67 |
| ▸ | HTR2A | P28223 | 4/20 | 0.67 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.67 |
| ▸ | HRH1 | P35367 | 4/20 | 0.67 |
| ▸ | DRD3 | P35462 | 4/20 | 0.67 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.67 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.67 |
| ▸ | CACNA1F | O60840 | 3/20 | 0.67 |
| ▸ | DRD4 | P21917 | 3/20 | 0.67 |
| ▸ | DRD5 | P21918 | 3/20 | 0.67 |
| ▸ | HRH2 | P25021 | 3/20 | 0.67 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.67 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.67 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.67 |
| ▸ | HTR6 | P50406 | 3/20 | 0.67 |
| ▸ | CACNA1D | Q01668 | 3/20 | 0.67 |
| ▸ | CACNA1S | Q13698 | 3/20 | 0.67 |
| ▸ | CACNA1C | Q13936 | 3/20 | 0.67 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.67 |
| ▸ | HTR2C | P28335 | 2/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5076783 | 0.87 | CACNA1F (0.70) | HTR7HTR2AADRA1AHRH1DRD3 | |
| SCHEMBL5076191 | 0.84 | CACNA1F (0.67) | HTR7HTR2AADRA1AHRH1DRD3 | |
| SCHEMBL5023656 | 0.84 | SCN5A (0.56) | HTR7HTR2AADRA1AHRH1DRD3 | |
| Difluanine SCHEMBL1813120 | 0.84 | SCN5A (0.59) | HTR7HTR2AADRA1AHRH1DRD3 | |
| Difluanine SCHEMBL28172554 | 0.83 | SCN5A (0.57) | HTR7HTR2AADRA1AHRH1DRD3 | |
| Difluanine SCHEMBL124263 | 0.83 | SCN5A (0.57) | HTR7HTR2AADRA1AHRH1DRD3 | |
| SCHEMBL5074793 | 0.82 | HTR7 (0.66) | HTR7HTR2AADRA1AHRH1DRD3 | |
| SCHEMBL5077507 | 0.82 | CACNA1F (0.66) | HTR7HTR2AADRA1AHRH1DRD3 | |
| SCHEMBL5080775 | 0.80 | CACNA1F (0.61) | HTR7HTR2AADRA1AHRH1DRD3 | |
| SCHEMBL5017480 | 0.80 | SLC6A3 (0.61) | HTR7HTR2AADRA1AHRH1DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040266784-A1 | Calcium channel inhibitors comprising benzhydril spaced from piperazine | ZALICUS PHARMACEUTICALS LTD. (CA) | 2004-12-30 | — | — | US | claimed |
| US-20080300262-A1 | Combination Therapy for Relief of Pain | ZALICUS PHARMACEUTICALS LTD. (CA) | 2008-12-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040266784-A1 | Calcium channel inhibitors comprising benzhydril spaced from piperazine | CACNA1C, CACNA1F, CACNA1D | HTR7 610/4885HTR2A 372/4885ADRA1A 1698/4885 |
| US-20080300262-A1 | Combination Therapy for Relief of Pain | CACNA1B, TRPV1, ORAI1 | HTR7 969/4885HTR2A 429/4885ADRA1A 485/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.